Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E. (Q45364853)

13 December 2017

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E. (English)

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13 December 2017

6

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13 December 2017

Stefan Mahrhold

1

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13 December 2017

Jasmin Strotmeier

2

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13 December 2017

Consuelo Garcia-Rodriguez

3

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13 December 2017

Jianlong Lou

4

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13 December 2017

James D Marks

5

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13 December 2017

Thomas Binz

7

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13 December 2017

language of work or name

English

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publication date

1 July 2013

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13 December 2017

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13 December 2017

453

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13 December 2017

1

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13 December 2017

37-47

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Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis

13 December 2017

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https://api.crossref.org/works/10.1042%2FBJ20130391

Crystal structure of botulinum neurotoxin type A and implications for toxicity

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Clostridial neurotoxins: mechanism of SNARE cleavage and outlook on potential substrate specificity reengineering

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxin: a marvel of protein design

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Cell entry strategy of clostridial neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Structural Analysis of Botulinum Neurotoxin Type G Receptor Binding,

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight into Cell Surface Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum Neurotoxin Serotype C Associates with Dual Ganglioside Receptors to Facilitate Cell Entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA,

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

How do tetanus and botulinum toxins bind to neuronal membranes?

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

SV2 is the protein receptor for botulinum neurotoxin A.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

SV2 mediates entry of tetanus neurotoxin into central neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Structural basis of cell surface receptor recognition by botulinum neurotoxin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Optimal docking area: a new method for predicting protein-protein interaction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20130391

Engineered domain-based assays to identify individual antibodies in oligoclonal combinations targeting the same protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130391

21 January 2018

Identifiers

DOI

10.1042/BJ20130391

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release_53nfki6zxveete4hvr2jktstvu

13 December 2017

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Fatcat

https://api.fatcat.wiki/v0/release/53nfki6zxveete4hvr2jktstvu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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