Fas ligand-mediated apoptosis in degenerative disorders of the brain (Q45292904)

11 December 2017

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title

Fas ligand-mediated apoptosis in degenerative disorders of the brain (English)

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11 December 2017

1

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11 December 2017

Lillian A Buhler

2

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11 December 2017

1 November 2003

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Journal of Clinical Immunology

11 December 2017

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11 December 2017

23

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11 December 2017

439-446

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11 December 2017

6

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https://scigraph.springernature.com/pub.10.1023/b:joci.0000010420.96419.a8

11 December 2017

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cites work

TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia.

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12 December 2020

Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.

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12 December 2020

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

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12 December 2020

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

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12 December 2020

Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory res

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12 December 2020

FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication

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Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

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12 December 2020

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

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Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

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12 December 2020

Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease

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12 December 2020

Hypoxia stimulates release of the soluble form of fas ligand that inhibits endothelial cell apoptosis

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12 December 2020

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

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12 December 2020

Soluble antigen therapy induces apoptosis of autoreactive T cells preferentially in the target organ rather than in the peripheral lymphoid organs.

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12 December 2020

Fas and Fas ligand: lpr and gld mutations

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12 December 2020

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

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12 December 2020

The CD95(APO-1/Fas) DISC and beyond

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12 December 2020

Inflammation of the brain in Alzheimer's disease: implications for therapy.

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12 December 2020

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier.

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12 December 2020

TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL.

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12 December 2020

Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice.

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12 December 2020

Fas system up-regulation in experimental autoimmune encephalomyelitis

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12 December 2020

Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity.

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12 December 2020

Anti-inflammatory agents in Alzheimer's disease

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12 December 2020

Immunological mechanisms and the spectrum of psychiatric syndromes in Alzheimer's disease

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12 December 2020

Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions.

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12 December 2020

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease

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12 December 2020

Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons.

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12 December 2020

In-vivo measurement of activated microglia in dementia

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12 December 2020

Abeta-generating enzymes: recent advances in beta- and gamma-secretase research

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12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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12 December 2020

Apoptosis mediators fasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS

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12 December 2020

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

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12 December 2020

The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system

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12 December 2020

Tumor necrosis factor-alpha converting enzyme

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12 December 2020

Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor

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12 December 2020

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

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12 December 2020

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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12 December 2020

Neuronal FasL induces cell death of encephalitogenic T lymphocytes

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12 December 2020

Fas ligand and Fas are expressed constitutively in human astrocytes and the expression increases with IL-1, IL-6, TNF-alpha, or IFN-gamma.

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12 December 2020

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons.

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12 December 2020

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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12 December 2020

Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo

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12 December 2020

Chemotactic activity of soluble Fas ligand against phagocytes

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12 December 2020

Inflammation and Alzheimer's disease

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12 December 2020

Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug

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12 December 2020

Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease

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12 December 2020

Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis.

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12 December 2020

Presence and significance of CD-95 (Fas/APO1) expression after spinal cord injury

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12 December 2020

Fas receptor and neuronal cell death after spinal cord ischemia

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12 December 2020

Upregulation of the apoptosis regulators cFLIP, CD95 and CD95 ligand in peripheral blood mononuclear cells in relapsing-remitting multiple sclerosis

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12 December 2020

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

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12 December 2020

Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790

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12 December 2020

Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: further evidence of apoptotic deletion of autoreactive T cells in the central nervous system

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12 December 2020

Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis

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12 December 2020

New concepts in the immunopathogenesis of multiple sclerosis

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12 December 2020

CD95-CD95L: can the brain learn from the immune system?

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12 December 2020

Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide

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12 December 2020

A targeted DNA vaccine encoding fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis

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12 December 2020

Stromelysin-1 (MMP-3) in synovial fluid of patients with rheumatoid arthritis has potential to cleave membrane bound Fas ligand

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12 December 2020

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

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12 December 2020

Cell death and immune privilege

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12 December 2020

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology

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12 December 2020

Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: a lesson from the mouse model.

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12 December 2020

CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance

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12 December 2020

Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.

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12 December 2020

CD95's deadly mission in the immune system

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12 December 2020

Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing

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12 December 2020

Fas ligand mediates activation-induced cell death in human T lymphocytes

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12 December 2020

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

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12 December 2020

Modulation of fas-ligand (Fas-L) on human microglial cells: an in vitro study

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12 December 2020

Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase

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12 December 2020

Microglia induce CD4 T lymphocyte final effector function and death

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12 December 2020

Acute neuronal apoptosis in a rat model of multiple sclerosis.

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12 December 2020

Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells

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12 December 2020

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

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12 December 2020

Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease.

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12 December 2020

Activation-induced apoptosis of autoreactive and alloreactive T lymphocytes in the target organ as a major mechanism of tolerance

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12 December 2020

Downregulation of Fas ligand by shedding

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12 December 2020

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

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12 December 2020

Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke.

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12 December 2020

Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease

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12 December 2020

10.1023/B:JOCI.0000010420.96419.A8

Identifiers

DOI

1 reference

PubMed ID

15031631

Dimensions Publication ID

11 December 2017

0 references

1 reference

PubMed ID

15031631