BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2A receptor is involved. (Q45291563)

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scientific article published on 27 February 2013

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English	BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2A receptor is involved.	scientific article published on 27 February 2013

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scholarly article

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23 February 2020

BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2A receptor is involved (English)

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23 February 2020

Huntington's disease

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Alberto Martire

1

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23 February 2020

Antonella Ferrante

4

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23 February 2020

Valentina Chiodi

5

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23 February 2020

author name string

Rita Pepponi

2

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23 February 2020

Maria Rosaria Domenici

3

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23 February 2020

Patrizia Popoli

6

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23 February 2020

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27 February 2013

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23 February 2020

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11

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Journal of Neurochemistry

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23 February 2020

125

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23 February 2020

2

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23 February 2020

225-235

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23 February 2020

Changes in expression of N-methyl-D-aspartate receptor subunits occur early in the R6/2 mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

The LTP Program: a data acquisition program for on-line analysis of long-term potentiation and other synaptic events

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

BDNF regulates the expression and traffic of NMDA receptors in cultured hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Generation and characterization of embryonic striatal conditionally immortalized ST14A cells

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Dopaminergic modulation of early signs of excitotoxicity in visualized rat neostriatal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

NMDA receptor function in mouse models of Huntington disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

BDNF modulation of NMDA receptors is activity dependent

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

NMDA receptor subunits: diversity, development and disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Influence of age on BDNF modulation of hippocampal synaptic transmission: interplay with adenosine A2A receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Behavioral and electrophysiological effects of the adenosine A2A receptor antagonist SCH 58261 in R6/2 Huntington's disease mice

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

ST14A cells have properties of a medium-size spiny neuron.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Influence of CGS 21680, a selective adenosine A(2A) receptor agonist, on NMDA receptor function and expression in the brain of Huntington's disease mice.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Activation of Trk neurotrophin receptors in the absence of neurotrophins

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Opposite effects of the A2A receptor agonist CGS21680 in the striatum of Huntington's disease versus wild-type mice.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Remodeling of striatal NMDA receptors by chronic A(2A) receptor blockade in Huntington's disease mice

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Triggering of BDNF facilitatory action on neuromuscular transmission by adenosine A2A receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Reduced activity of cortico-striatal fibres in the R6/2 mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Huntington disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Role of brain-derived neurotrophic factor in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12177

21 January 2018

Identifiers

10.1111/JNC.12177

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23363456%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23363456%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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