The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation (Q45242015)

11 December 2017

The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation (English)

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11 December 2017

8

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11 December 2017

Erwin Gäbele

1

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11 December 2017

Shimon Reif

2

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11 December 2017

Shigeki Tsukada

3

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11 December 2017

Ramon Bataller

4

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11 December 2017

Yutaka Yata

5

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11 December 2017

Terry Morris

6

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11 December 2017

Laura W Schrum

7

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11 December 2017

Richard A Rippe

9

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11 December 2017

language of work or name

English

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publication date

26 January 2005

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Journal of Biological Chemistry

11 December 2017

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11 December 2017

280

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11 December 2017

13374-13382

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11 December 2017

14

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

11 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cytokine receptors and signaling in hepatic stellate cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cellular function of p70S6K: a role in regulating cell motility

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Ribosomal S6 kinase signaling and the control of translation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

The modular phosphorylation and activation of p70s6k.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Regulation of translation initiation by FRAP/mTOR

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409444200

Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cell cycle control of DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Heat-induced G1 arrest is dependent on p53 function but not on RB dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409444200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409444200

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11 December 2017

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