The modular phosphorylation and activation of p70s6k. (Q34434557)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9247127%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

The modular phosphorylation and activation of p70s6k (English)

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5 November 2019

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1

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5 November 2019

author name string

G Thomas

series ordinal

2

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5 November 2019

publication date

1 June 1997

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5 November 2019

language of work or name

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5 November 2019

volume

410

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5 November 2019

issue

1

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5 November 2019

page(s)

78-82

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publication type of scholarly work

5 November 2019

review article

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MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

cites work

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

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Retinoblastoma protein. Another role rolls in.

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Mitogenesis and protein synthesis: a role for ribosomal protein S6 phosphorylation?

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Identification and characterization of a mitogen-activated S6 kinase

21 January 2018

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Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily

21 January 2018

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Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase

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Activation of p70/p85 S6 kinase by a pathway independent of p21ras

21 January 2018

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Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

21 January 2018

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Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

21 January 2018

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Multiple independent inputs are required for activation of the p70 S6 kinase

21 January 2018

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

21 January 2018

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 January 2018

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Control of p70 s6 kinase by kinase activity of FRAP in vivo

21 January 2018

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 January 2018

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Structural and functional analysis of pp70S6k

21 January 2018

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The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

21 January 2018

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

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Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

21 January 2018

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21 January 2018

Phosphoinositide kinases

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Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

21 January 2018

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Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

21 January 2018

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21 January 2018

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The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

21 January 2018

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p70s6k function is essential for G1 progression

21 January 2018

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The growth of research on protein phosphorylation

21 January 2018

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Nuclear localization of p85s6k: functional requirement for entry into S phase.

7 January 2021

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A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells

7 January 2021

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The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

7 January 2021

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

7 January 2021

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Normal Activation of P70 S6 Kinase by Insulin in Cells Overexpressing Dominant Negative 85-kDa Subunit of Phosphoinositide 3-Kinase

7 January 2021

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7 January 2021

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10.1016/S0014-5793(97)00323-2

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9247127%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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