Exogenous activation of BMP-2 signaling overcomes TGFβ-mediated inhibition of osteogenesis in Marfan embryonic stem cells and Marfan patient-specific induced pluripotent stem cells. (Q45125619)

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scientific article published in December 2012

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English	Exogenous activation of BMP-2 signaling overcomes TGFβ-mediated inhibition of osteogenesis in Marfan embryonic stem cells and Marfan patient-specific induced pluripotent stem cells.	scientific article published in December 2012

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9 March 2020

Exogenous activation of BMP-2 signaling overcomes TGFβ-mediated inhibition of osteogenesis in Marfan embryonic stem cells and Marfan patient-specific induced pluripotent stem cells (English)

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9 March 2020

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9 March 2020

author name string

Natalina Quarto

1

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9 March 2020

Shuli Li

2

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9 March 2020

Michael T Longaker

4

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9 March 2020

publication date

1 December 2012

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9 March 2020

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9 March 2020

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9 March 2020

12

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9 March 2020

2709-2719

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9 March 2020

Recent progress towards a molecular understanding of Marfan syndrome

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

The molecular genetics of Marfan syndrome and related disorders

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

The Marfan Syndrome: Diagnosis and Management

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Extracellular control of TGFbeta signalling in vascular development and disease

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https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Marfan phenotype variability in a family segregating a missense mutation in the epidermal growth factor-like motif of the fibrillin gene

1 reference

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21 January 2018

Mutations in the human gene for fibrillin-1 (FBN1) in the Marfan syndrome and related disorders

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

De novo 15q21.1q21.2 deletion identified through FBN1 MLPA and refined by 244K array-CGH in a female teenager with incomplete Marfan syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

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https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome

1 reference

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21 January 2018

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

1 reference

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21 January 2018

Aneurysm syndromes caused by mutations in the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Mutations in transforming growth factor-beta receptor type II cause familial thoracic aortic aneurysms and dissections

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Heterozygous TGFBR2 mutations in Marfan syndrome

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Multi-exon deletions of the FBN1 gene in Marfan syndrome

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Differential expression of specific FGF ligands and receptor isoforms during osteogenic differentiation of mouse Adipose-derived Stem Cells (mASCs) recapitulates the in vivo osteogenic pattern

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Gene profiling of cells expressing different FGF-2 forms

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs).

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Nonintegrating knockdown and customized scaffold design enhances human adipose-derived stem cells in skeletal repair.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

TGFbeta in Cancer

1 reference

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21 January 2018

The two faces of transforming growth factor beta in carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

A comparative analysis of the osteogenic effects of BMP-2, FGF-2, and VEGFA in a calvarial defect model.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Differential effects of transforming growth factor-beta on the synthesis of extracellular matrix proteins by normal fetal rat calvarial bone cell populations

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

BMP7 antagonizes TGF-beta -dependent fibrogenesis in mesangial cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Molecular interaction of BMP-4, TGF-beta, and estrogens in lactotrophs: impact on the PRL promoter

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Interaction of TGFβ and BMP signaling pathways during chondrogenesis

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Transforming Growth Factor {beta} Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling

1 reference

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21 January 2018

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

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21 January 2018

Noggin expands neural stem cells in the adult hippocampus

1 reference

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21 January 2018

Noggin maintains pluripotency of human embryonic stem cells grown on Matrigel

1 reference

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21 January 2018

TGF-beta signaling in vascular biology and dysfunction

1 reference

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21 January 2018

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

1 reference

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21 January 2018

A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1250

21 January 2018

Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).

1 reference

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21 January 2018

Diseases in a dish: modeling human genetic disorders using induced pluripotent cells

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21 January 2018

Concise review: Embryonic stem cells versus induced pluripotent stem cells: the game is on.

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21 January 2018

Partial sequence of a candidate gene for the Marfan syndrome

1 reference

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21 January 2018

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