The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia. (Q45062542)

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24 March 2020

title

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia (English)

1 reference

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7

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Charles G. Mullighan

39

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Yu Liu

1

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Stanley Pounds

9

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Michael Rusch

15

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Malcolm A Smith

19

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Kimberly P Dunsmore

31

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24 March 2020

25

Nyla A Heerema

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24 March 2020

28

Cheryl L Willman

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24 March 2020

author name string

John Easton

2

1 reference

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24 March 2020

Ying Shao

3

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24 March 2020

Jamie Maciaszek

4

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24 March 2020

Zhaoming Wang

5

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24 March 2020

Mark R Wilkinson

6

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Michael Edmonson

8

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Lei Shi

10

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24 March 2020

Xin Zhou

11

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24 March 2020

Xiaotu Ma

12

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Edgar Sioson

13

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Yongjin Li

14

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Pankaj Gupta

16

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Deqing Pei

17

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Cheng Cheng

18

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Jaime Guidry Auvil

20

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Daniela S Gerhard

21

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Mary V Relling

22

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Naomi J Winick

23

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Andrew J Carroll

24

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Elizabeth Raetz

26

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Meenakshi Devidas

27

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Richard C Harvey

29

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William L Carroll

30

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Stuart S Winter

32

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Brent L Wood

33

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Brian P Sorrentino

34

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James R Downing

35

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Mignon L Loh

36

1 reference

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Jinghui Zhang

38

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Stephen P Hunger

37

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24 March 2020

language of work or name

English

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publication date

3 July 2017

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24 March 2020

1 reference

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24 March 2020

volume

49

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24 March 2020

page(s)

1211-1218

1 reference

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24 March 2020

issue

8

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https://scigraph.springernature.com/pub.10.1038/ng.3909

24 March 2020

exact match

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

25 May 2018

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Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

25 May 2018

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The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

25 May 2018

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Molecular pathogenesis of T-cell leukaemia and lymphoma

25 May 2018

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Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

25 May 2018

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

25 May 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

25 May 2018

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

25 May 2018

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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

25 May 2018

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A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

25 May 2018

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Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia

25 May 2018

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The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

25 May 2018

1 reference

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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

25 May 2018

1 reference

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Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

25 May 2018

1 reference

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Evaluation of survival data and two new rank order statistics arising in its consideration

25 May 2018

1 reference

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lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Acute Lymphoblastic Leukemia in Children.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2)

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

15 August 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

3 November 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535770

Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15

1 December 2018

1 reference

7 January 2021

Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias

1 reference

7 January 2021

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis

1 reference

7 January 2021

Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

Mutational landscape of adult ETP-ALL.

1 reference

7 January 2021

Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice

1 reference

7 January 2021

Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28671688

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.3909

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28671688%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 March 2020

1090336724

0 references

Fatcat ID

release_hajndki7s5bqzd2w4sd4kas6pa

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hajndki7s5bqzd2w4sd4kas6pa

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28671688%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference