The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. (Q44957894)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27856798%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

title

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity (English)

1 reference

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27 March 2020

1 reference

10

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27 March 2020

Natacha Olieric

12

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27 March 2020

Michel O Steinmetz

22

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27 March 2020

2

Joseph Tcherkezian

1 reference

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27 March 2020

author name string

Michal Wieczorek

1

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27 March 2020

Cynthia Bernier

3

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27 March 2020

Andrea E Prota

4

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27 March 2020

Sami Chaaban

5

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27 March 2020

Yannève Rolland

6

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27 March 2020

Claude Godbout

7

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27 March 2020

Mark A Hancock

8

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Joseph C Arezzo

9

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Cecilia Rocha

11

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27 March 2020

Anita Hall

13

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27 March 2020

Hui Ding

14

1 reference

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27 March 2020

Alexandre Bramoullé

15

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Matthew G Annis

16

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George Zogopoulos

17

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Patrick G Harran

18

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Thomas M Wilkie

19

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Rolf A Brekken

20

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Peter M Siegel

21

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Gordon C Shore

23

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Gary J Brouhard

24

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Anne Roulston

25

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language of work or name

English

0 references

publication date

1 November 2016

1 reference

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Science Translational Medicine

27 March 2020

published in

1 reference

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volume

8

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27 March 2020

page(s)

365ra159

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issue

365

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Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics

27 March 2020

cites work

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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

25 May 2018

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Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends

25 May 2018

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25 May 2018

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The determinants that govern microtubule assembly from the atomic structure of GTP-tubulin

25 May 2018

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The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

25 May 2018

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Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules

25 May 2018

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25 May 2018

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25 May 2018

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Analysis of microtubule dynamic instability using a plus-end growth marker

25 May 2018

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25 May 2018

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Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly

25 May 2018

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25 May 2018

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Cell death by mitotic catastrophe: a molecular definition

25 May 2018

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Microtubules as a target for anticancer drugs

25 May 2018

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Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), the Robert A. Wel

25 May 2018

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The spindle checkpoint: structural insights into dynamic signalling

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.

25 May 2018

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Aggregation of microtubule subunit protein. Effects of divalent cations, colchicine, and vinblastine

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Doublecortin recognizes the longitudinal curvature of the microtubule end and lattice.

15 August 2018

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A specific inhibitor of CDK1, RO-3306, reversibly arrests meiosis during in vitro maturation of porcine oocytes

15 August 2018

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A synthetic dolastatin 10 analogue suppresses microtubule dynamics, inhibits cell proliferation, and induces apoptotic cell death

15 August 2018

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Mitosis is not a key target of microtubule agents in patient tumors.

15 August 2018

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Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.

15 August 2018

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Structural basis for the regulation of tubulin by vinblastine

15 August 2018

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Morphological and morphometric analysis of paclitaxel and docetaxel-induced peripheral neuropathy in rats

15 August 2018

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Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

15 August 2018

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Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer.

15 August 2018

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Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin

15 August 2018

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15 August 2018

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Kin I kinesins are microtubule-destabilizing enzymes

15 August 2018

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Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules

15 August 2018

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15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291303

Chemotherapy-induced peripheral neuropathy

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27856798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The thermodynamics of vinca alkaloid-induced tubulin spirals formation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27856798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Physical aspects of the growth and regulation of microtubule structures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27856798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.AAG1093

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27856798%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27856798%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference