Molecular mechanism of action of microtubule-stabilizing anticancer agents (Q27683695)

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21 February 2020

title

Molecular mechanism of action of microtubule-stabilizing anticancer agents (English)

1 reference

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21 February 2020

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5

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21 February 2020

Michel O Steinmetz

7

1 reference

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21 February 2020

author name string

Andrea E Prota

1

1 reference

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21 February 2020

Katja Bargsten

2

1 reference

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21 February 2020

Didier Zurwerra

3

1 reference

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21 February 2020

Jessica J Field

4

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21 February 2020

Karl-Heinz Altmann

6

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21 February 2020

language of work or name

English

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publication date

3 January 2013

1 reference

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21 February 2020

1 reference

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21 February 2020

volume

339

1 reference

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21 February 2020

issue

6119

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21 February 2020

page(s)

587-590

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Microtubule-binding agents: a dynamic field of cancer therapeutics

21 February 2020

cites work

1 reference

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Structure of the alpha beta tubulin dimer by electron crystallography

21 April 2017

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A TOG: -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

21 April 2017

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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

21 April 2017

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Refined structure of alpha beta-tubulin at 3.5 A resolution

21 April 2017

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Template-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolution

21 April 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

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Coot: model-building tools for molecular graphics

21 April 2017

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MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

21 April 2017

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Linking Crystallographic Model and Data Quality

21 April 2017

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Promotion of microtubule assembly in vitro by taxol

21 April 2017

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Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition.

21 January 2018

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Thermodynamics of ligand-induced assembly of tubulin.

21 January 2018

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Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

21 January 2018

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High-resolution model of the microtubule

21 January 2018

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The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography

21 January 2018

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Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules

21 January 2018

1 reference

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Structural Basis of the Activity of the Microtubule-Stabilizing Agent Epothilone A Studied by NMR Spectroscopy in Solution

21 January 2018

1 reference

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Taxol allosterically alters the dynamics of the tubulin dimer and increases the flexibility of microtubules

21 January 2018

1 reference

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Straight GDP-tubulin protofilaments form in the presence of taxol

21 January 2018

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Insights into the mechanism of microtubule stabilization by Taxol.

21 January 2018

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The chemistry and biology of epothilones--the wheel keeps turning.

21 January 2018

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Ixabepilone in combination with capecitabine and as monotherapy for treatment of advanced breast cancer refractory to previous chemotherapies

21 January 2018

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Total synthesis of (-)-zampanolide and structure-activity relationship studies on (-)-dactylolide derivatives.

21 January 2018

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Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1230582

2 references

Consolidated OpenCitations Corpus – April 2017

352156

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23287720%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

352156

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

352156

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23287720%20AND%20SRC:MED&resulttype=core&format=json