Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition (Q44762646)

6 December 2017

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition (English)

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6 December 2017

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3

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6 December 2017

Conrad C Alano

1

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PubMed ID

14960594

6 December 2017

Weihai Ying

series ordinal

2

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PubMed ID

14960594

6 December 2017

language of work or name

English

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publication date

11 February 2004

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Journal of Biological Chemistry

6 December 2017

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6 December 2017

279

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6 December 2017

18895-18902

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6 December 2017

18

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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

6 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

Structure and function of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondrial permeability transition in acute neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Cyclosporin A enhances survival, ameliorates brain damage, and prevents secondary mitochondrial dysfunction after a 30-minute period of transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondrial control of nuclear apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Connexin 43 hemi channels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

Astrocytes protect neurons from neurotoxic injury by serum glutamate.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Analysis of mitochondrial morphology and function with novel fixable fluorescent stains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Imaging the mitochondrial permeability transition pore in intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

The mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Analysis of ADP-ribose polymer sizes in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Potential role of calcineurin for brain ischemia and traumatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Pathophysiological relevance of mitochondria in NAD(+) metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Mitochondria are morphologically and functionally heterogeneous within cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

PARP is important for genomic stability but dispensable in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313329200

Increased poly(ADP-ribosyl)ation in intact cells by cisplatin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2+ and Oxidant Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313329200

21 January 2018

Identifiers

DOI

10.1074/JBC.M313329200

1 reference

6 December 2017

1 reference

PubMed ID

14960594