Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation (Q44539325)

4 December 2017

Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation (English)

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4 December 2017

12

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4 December 2017

Terence J Campbell

9

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Margaret Sunde

object named as

Margaret Sunde

3

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author name string

Allan M Torres

1

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4 December 2017

Paramjit S Bansal

2

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4 December 2017

Catherine E Clarke

4

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4 December 2017

Jane A Bursill

5

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4 December 2017

David J Smith

6

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4 December 2017

Asne Bauskin

7

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4 December 2017

Samuel N Breit

8

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4 December 2017

Paul F Alewood

10

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4 December 2017

Philip W Kuchel

11

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4 December 2017

language of work or name

English

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publication date

5 August 2003

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Journal of Biological Chemistry

4 December 2017

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4 December 2017

278

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4 December 2017

43

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4 December 2017

42136-42148

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

4 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

21 January 2018

I(Kr): the hERG channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The long QT syndromes: genetic basis and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Molecular and cellular mechanisms of cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

HERG K+ channels: friend and foe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

A family of potassium channel genes related to eag in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Fast inactivation causes rectification of the IKr channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The inward rectification mechanism of the HERG cardiac potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Molecular determinants of dofetilide block of HERG K+ channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Structural and functional role of the extracellular s5-p linker in the HERG potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The moving parts of voltage-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

A structural basis for drug-induced long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Allosteric effects of mutations in the extracellular S5-P loop on the gating and ion permeation properties of the hERG potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Potassium channels: from scorpion venoms to high-resolution structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

An ERG channel inhibitor from the scorpion Buthus eupeus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Crystal structure and mechanism of a calcium-gated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

X-ray structure of a voltage-dependent K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Crystal structure of the potassium channel KirBac1.1 in the closed state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Stability of membrane proteins: relevance for the selection of appropriate methods for high-resolution structure determinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Potassium channel structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Intrinsic helical propensities and stable secondary structure in a membrane-bound fragment (S4) of the shaker potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Torsion angle dynamics for NMR structure calculation with the new program DYANA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

Extracellular sodium interacts with the HERG channel at an outer pore site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

State-dependent barium block of wild-type and inactivation-deficient HERG channels in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212824200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212824200

1 reference

4 December 2017

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