Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate (Q35028771)

5 August 2017

title

Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate (English)

1 reference

5 August 2017

B D Walker

1

1 reference

5 August 2017

S M Valenzuela

2

1 reference

5 August 2017

C B Singleton

3

1 reference

5 August 2017

H Tie

4

1 reference

5 August 2017

J A Bursill

5

1 reference

5 August 2017

K R Wyse

6

1 reference

5 August 2017

M R Qiu

7

1 reference

5 August 2017

S N Breit

8

1 reference

5 August 2017

T J Campbell

9

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5 August 2017

language of work or name

English

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publication date

1 May 1999

1 reference

British Journal of Pharmacology

5 August 2017

published in

1 reference

5 August 2017

volume

127

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5 August 2017

issue

1

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5 August 2017

page(s)

243-251

1 reference

A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Molecular determinants of dofetilide block of HERG K+ channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

A minK-HERG complex regulates the cardiac potassium current I(Kr)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Fast inactivation causes rectification of the IKr channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

High affinity open channel block by dofetilide of HERG expressed in a human cell line.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

The inward rectification mechanism of the HERG cardiac potassium channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

K+ currents and K+ channel mRNA in cultured atrial cardiac myocytes (AT-1 cells).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Voltage- and time-dependent block by perhexiline of K+ currents in human atrium and in cells expressing a Kv1.5-type cloned channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Proceedings: Evaluation of anti-arrhythmic efficacy of perhexiline maleate in ambulatory patients by Holter monitoring

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Proceedings: Clinical evaluation of perhexiline maleate in the treatment of chronic cardiac arrhythmias of patients with coronary heart disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Inhibitory effects of some cyclohexylaralkylamines related to perhexiline on sodium influx, binding of [3H]batrachotoxinin A 20-α-benzoate and [3H]nitrendipine and on guinea pig left atria contractions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Torsade de pointes associated with perhexiline maleate therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Efficacy and safety of perhexiline maleate in refractory angina. A double-blind placebo-controlled clinical trial of a novel antianginal agent

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Supression of ventricular extrasystoles by perhexiline

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Use-dependent block and use-dependent unblock of the delayed rectifier K+ current by almokalant in rabbit ventricular myocytes.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702502

Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702502

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565989

Proceedings: Effects of perhexiline on the electrophysiologic activity of mammalian heart

25 October 2018

1 reference

12 December 2020

Vesnarinone prolongs action potential duration without reverse frequency dependence in rabbit ventricular muscle by blocking the delayed rectifier K+ current

1 reference

12 December 2020

Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics

1 reference

12 December 2020

Understanding consequences of concurrent therapies

1 reference

12 December 2020

Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia

1 reference

12 December 2020

Is perhexiline essential for the optimal management of angina pectoris?

1 reference

12 December 2020

Perhexiline improves symptomatic status in elderly patients with severe aortic stenosis

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0702502

1 reference

release_pzf7eqduh5dkjjn3tpuxcxzwgu

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pzf7eqduh5dkjjn3tpuxcxzwgu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1565989

1 reference

5 August 2017

1 reference