The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor (Q28295368)

GOA release 2020-03-11

author name string

D. Soppet

1

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E. Escandon

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J. Maragos

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D. S. Middlemas

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S. W. Reid

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J. Blair

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L. E. Burton

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B. R. Stanton

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D. R. Kaplan

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T. Hunter

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K. Nikolics

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L. F. Parada

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https://api.elsevier.com/content/article/PII:009286749190396G?httpAccept=text/xml

20 October 2022

publication date

31 May 1991

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language of work or name

English

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work available at URL

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https://api.elsevier.com/content/article/PII:009286749190396G?httpAccept=text/plain

20 October 2022

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65

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issue

5

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page(s)

895-903

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Trophic factors and neuronal survival

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High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

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Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

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The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

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The trk proto-oncogene encodes a receptor for nerve growth factor

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The nerve growth factor 35 years later

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Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

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