Regulating the neoplastic phenotype using engineered transcriptional repressors (Q44226104)

1 December 2017

Regulating the neoplastic phenotype using engineered transcriptional repressors (English)

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1 December 2017

W J Fredericks

1

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1 December 2017

K Ayyanathan

series ordinal

2

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1 December 2017

F J Rauscher

series ordinal

3

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1 December 2017

language of work or name

English

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publication date

1 January 2001

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1 December 2017

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1 December 2017

162 Suppl

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1 December 2017

S23-S32

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A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Modular structure of transcription factors: implications for gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

RNA polymerase II as a control panel for multiple coactivator complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Understanding gene and allele function with two-hybrid methods.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Chromosomal abnormalities and tumor development: from genes to therapeutic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Chromosomal translocations in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Gene fusions encoding chimaeric transcription factors in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Active repression mechanisms of eukaryotic transcription repressors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Repression and activation by multiprotein complexes that alter chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Repression: targeting the heart of the matter

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Progress in transcriptionally targeted and regulatable vectors for genetic therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Tissue-selective expression of dominant-negative proteins for the regulation of vascular smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

KAP-1, a novel corepressor for the highly conserved KRAB repression domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Krüppel-associated boxes are potent transcriptional repression domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Pax genes and organogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Negative regulation of the forkhead transcription factor FKHR by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Transcriptional repression mediated by the WT1 Wilms tumor gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Active repression of transcription by the engrailed homeodomain protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Positive and negative regulation of endogenous genes by designed transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

A fusion protein of the estrogen receptor (ER) and nuclear receptor corepressor (NCoR) strongly inhibits estrogen-dependent responses in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Dominant interfering alleles define a role for c-Myb in T-cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Inhibition of Tat-mediated transactivation and HIV replication with Tat mutant and repressor domain fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Transiently transfected and stably integrated HIV-1 LTR responds differentially to the silencing activity of the Krüppel-associated box (KRAB) transcriptional repressor domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

A dominant interfering Myb mutant causes apoptosis in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Inhibition of human hematopoietic tumor formation by targeting a repressor Myb-KRAB to DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Retinoblastoma protein tethered to promoter DNA represses TBP-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Zinc finger peptides for the regulation of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Zinc finger proteins as designer transcription factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Suppression of gene expression by tethering KRAB domain to promoter of ER target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900649-2

7 January 2021

10.1016/S0304-3835(00)00649-2

Identifiers

DOI

1 reference

release_aqnironixrgk7h32cm575bx3bu

1 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/aqnironixrgk7h32cm575bx3bu

24 November 2022

mapped directly with Wikidata item

1 reference