Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. (Q43646347)

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5 January 2020

title

Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells (English)

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5 January 2020

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2

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Jacques-Antoine Haefliger

5 January 2020

11

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5 January 2020

Mitsunori Fukuda

5

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5 January 2020

Amar Abderrahmani

7

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5 January 2020

Pierre Maechler

10

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5 January 2020

author name string

D Martin

1

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5 January 2020

G Chaffard

3

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5 January 2020

D Caille

4

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5 January 2020

R Regazzi

6

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5 January 2020

G Waeber

8

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5 January 2020

P Meda

9

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5 January 2020

publication date

3 April 2008

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5 January 2020

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5 January 2020

volume

51

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5 January 2020

issue

8

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5 January 2020

page(s)

1429-1439

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https://scigraph.springernature.com/pub.10.1007/s00125-008-0984-1

5 January 2020

exact match

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Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis

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Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor

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Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

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Secretory granule exocytosis

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Activation of the KATPchannel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH

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Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

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Identification of potential target genes for the neuron-restrictive silencer factor

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The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype

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Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis

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A genetic screen for candidate tumor suppressors identifies REST

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Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.

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Multiple forms of "kiss-and-run" exocytosis revealed by evanescent wave microscopy

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ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis

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Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.

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Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells

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12 December 2020

Requirement for N-ethylmaleimide-sensitive factor for exocytosis of insulin-containing secretory granules in pancreatic beta-cells

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12 December 2020

Glucose represses connexin36 in insulin-secreting cells.

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12 December 2020

Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells

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12 December 2020

Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene

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12 December 2020

The neuron-restrictive silencer element: a dual enhancer/silencer crucial for patterned expression of a nicotinic receptor gene in the brain

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12 December 2020

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

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12 December 2020

Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines

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12 December 2020

Synaptotagmin V and IX isoforms control Ca2+ -dependent insulin exocytosis.

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12 December 2020

The calcium-sensing protein synaptotagmin 7 is expressed on different endosomal compartments in endocrine, neuroendocrine cells or neurons but not on large dense core vesicles

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12 December 2020

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions.

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12 December 2020

Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin

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12 December 2020

Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation

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12 December 2020

Neuronal traits are required for glucose-induced insulin secretion

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12 December 2020

Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta -cell

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12 December 2020

Neural specific expression of the m4 muscarinic acetylcholine receptor gene is mediated by a RE1/NRSE-type silencing element

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12 December 2020

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

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12 December 2020

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

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12 December 2020

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

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12 December 2020

The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1)

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12 December 2020

Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment

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12 December 2020

Synaptotagmin IV regulates glial glutamate release

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12 December 2020