Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor (Q34097162)

31 July 2017

Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor (English)

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31 July 2017

4

David A Richards

1 reference

31 July 2017

Ping Wang

1

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31 July 2017

Michael C Chicka

series ordinal

2

1 reference

31 July 2017

Akhil Bhalla

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3

1 reference

31 July 2017

Edwin R Chapman

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5

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

Molecular and Cellular Biology

31 July 2017

1 reference

31 July 2017

25

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31 July 2017

8693-8702

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31 July 2017

19

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describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1265757/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis.

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Synaptotagmin VII is targeted to dense-core vesicles and regulates their Ca2+ -dependent exocytosis in PC12 cells.

5 July 2018

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Synaptotagmins are trafficked to distinct subcellular domains including the postsynaptic compartment.

5 July 2018

1 reference

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Synaptotagmin gene content of the sequenced genomes

5 July 2018

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N-glycosylation is essential for vesicular targeting of synaptotagmin 1.

5 July 2018

1 reference

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Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling

5 July 2018

1 reference

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Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells

5 July 2018

1 reference

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Killing the messenger: short RNAs that silence gene expression

5 July 2018

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Visualization of synaptotagmin I oligomers assembled onto lipid monolayers.

5 July 2018

1 reference

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Synaptotagmin: a Ca(2+) sensor that triggers exocytosis?

5 July 2018

1 reference

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Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human

5 July 2018

1 reference

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Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis

5 July 2018

1 reference

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Evidence for two distinct processes in the final stages of neurotransmitter release as detected by binomial analysis in calcium and strontium solutions

5 July 2018

1 reference

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Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I.

5 July 2018

1 reference

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Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells

5 July 2018

1 reference

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The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

The C2B domain of synaptotagmin is a Ca(2+)-sensing module essential for exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synaptotagmin III/VII isoforms mediate Ca2+-induced insulin secretion in pancreatic islet beta -cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of lysosomes in fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synthesis degradation, and subcellular localization of synaptotagmin IV, a neuronal immediate early gene product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Presynaptic strontium dynamics and synaptic transmission

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

SNAREpins: minimal machinery for membrane fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Functional properties of multiple synaptotagmins in brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Calcium dependence of the rate of exocytosis in a synaptic terminal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Two components of transmitter release at a central synapse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Regulated secretion. Helper proteins for neuroendocrine secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Identification of a nonneuronal isoform of synaptotagmin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Distinct Ca2+ and Sr2+ binding properties of synaptotagmins. Definition of candidate Ca2+ sensors for the fast and slow components of neurotransmitter release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

The biogenesis of lysosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Synaptotagmin: a membrane constituent of neuropeptide-containing large dense-core vesicles

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265757

Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes

28 October 2018

1 reference

12 December 2020

Probing fundamental aspects of synaptic transmission with strontium

1 reference

12 December 2020

Calcium sensitivity of glutamate release in a calyx-type terminal

1 reference

12 December 2020

Intracellular calcium dependence of transmitter release rates at a fast central synapse

1 reference

12 December 2020

Ion selectivities of the Ca(2+) sensors for exocytosis in rat phaeochromocytoma cells

1 reference

12 December 2020

Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner

1 reference

12 December 2020

10.1128/MCB.25.19.8693-8702.2005

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference