Ribavirin modulates the conversion of human CD4(+) CD25(-) T cell to CD4(+) CD25(+) FOXP3(+) T cell via suppressing interleukin-10-producing regulatory T cell (Q43596899)

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English	Ribavirin modulates the conversion of human CD4(+) CD25(-) T cell to CD4(+) CD25(+) FOXP3(+) T cell via suppressing interleukin-10-producing regulatory T cell	scientific article

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scholarly article

1 reference

Europe PubMed Central

25 November 2017

Ribavirin modulates the conversion of human CD4(+) CD25(-) T cell to CD4(+) CD25(+) FOXP3(+) T cell via suppressing interleukin-10-producing regulatory T cell (English)

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Europe PubMed Central

25 November 2017

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author name string

Tamaki Kobayashi

1

1 reference

Europe PubMed Central

25 November 2017

Katsuhisa Nakatsuka

2

1 reference

Europe PubMed Central

25 November 2017

Masumi Shimizu

3

1 reference

Europe PubMed Central

25 November 2017

Hideto Tamura

4

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Europe PubMed Central

25 November 2017

Eiji Shinya

5

1 reference

Europe PubMed Central

25 November 2017

Masanori Atsukawa

6

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Europe PubMed Central

25 November 2017

Hirotomo Harimoto

7

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Europe PubMed Central

25 November 2017

Hidemi Takahashi

8

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Europe PubMed Central

25 November 2017

Choitsu Sakamoto

9

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Europe PubMed Central

25 November 2017

publication date

1 November 2012

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Europe PubMed Central

25 November 2017

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Europe PubMed Central

25 November 2017

137

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Europe PubMed Central

25 November 2017

3

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Europe PubMed Central

25 November 2017

259-270

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Europe PubMed Central

25 November 2017

Regulatory T cells and inhibitory cytokines in autoimmunity

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Regulatory T cells: friend or foe in immunity to infection?

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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Regulatory T cells and immune tolerance

1 reference

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Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

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Natural versus adaptive regulatory T cells

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

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Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.

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In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

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21 January 2018

Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells

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CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses

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Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

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Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

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Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

1 reference

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Ribavirin, viramidine and adenosine-deaminase-catalysed drug activation: implication for nucleoside prodrug design

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Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group

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The antiviral compound ribavirin modulates the T helper (Th) 1/Th2 subset balance in hepatitis B and C virus-specific immune responses

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Ribavirin enhancement of hepatitis C virus core antigen-specific type 1 T helper cell response correlates with the increased IL-12 level

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Ribavirin downmodulates inducible costimulator on CD4+ T cells and their interleukin-10 secretion to assist in hepatitis C virus clearance

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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21 January 2018

Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile.

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21 January 2018

Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases

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21 January 2018

The Family of IL-10-secreting CD4+ T cells

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Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

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21 January 2018

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

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The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors

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The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

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Progression of fibrosis in chronic hepatitis C.

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Immunopathogenesis in hepatitis C virus cirrhosis

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Adaptive immune responses in acute and chronic hepatitis C virus infection

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Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.

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Elevated CD4+/CD25+ T cell frequency and function during acute hepatitis C presage chronic evolution.

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Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection

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Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C

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Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

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Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

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10.1111/IMM.12005

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Europe PubMed Central

25 November 2017

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1 reference

Europe PubMed Central

25 November 2017

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