Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog (Q43596664)

25 November 2017

title

Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog (English)

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25 November 2017

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Weisman R

1

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25 November 2017

Finkelstein S

series ordinal

2

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25 November 2017

Choder M

series ordinal

3

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25 November 2017

language of work or name

English

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publication date

2 May 2001

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Journal of Biological Chemistry

25 November 2017

published in

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25 November 2017

volume

276

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25 November 2017

issue

27

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25 November 2017

page(s)

24736-24742

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Peptidylproline cis-trans-isomerases: immunophilins

25 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Immunophilins: switched on protein binding domains?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Hypertrophic cardiomyopathy associated with tacrolimus in paediatric transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Catalysis of protein folding by prolyl isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Functional association of cyclophilin A with HIV-1 virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Specific incorporation of cyclophilin A into HIV-1 virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

The TOR signalling pathway and growth control in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

TOR controls translation initiation and early G1 progression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Rapamycin specifically interferes with the developmental response of fission yeast to starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Fusion of a fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

High efficiency transformation ofSchizosaccharomyces pombeby electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

A set of vectors with a tetracycline-regulatable promoter system for modulated gene expression in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Reduction in the intracellular cAMP level triggers initiation of sexual development in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Relationship between the subcellular localization and structures of catalytic domains of FKBP-type PPIases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

The gene for cyclophilin (peptidyl-prolyl cis-trans isomerase) from Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

TOR, a central controller of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Characterization of an exchange reaction between soluble FKBP-12 and the FKBP.ryanodine receptor complex. Modulation by FKBP mutants deficient in peptidyl-prolyl isomerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Signal-transduction cascades as targets for therapeutic intervention by natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

FKBP12 is a negative regulator of transforming growth factor-beta receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Thiamine-repressible expression vectors pREP and pRIP for fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102090200

21 January 2018

Identifiers

DOI

10.1074/JBC.M102090200

1 reference

25 November 2017

1 reference