Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. (Q43566798)

24 November 2017

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. (English)

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24 November 2017

Bunnell SC

1

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24 November 2017

Kapoor V

2

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24 November 2017

Trible RP

3

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24 November 2017

Zhang W

4

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24 November 2017

Samelson LE

5

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24 November 2017

language of work or name

English

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publication date

1 March 2001

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24 November 2017

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24 November 2017

14

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24 November 2017

3

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24 November 2017

315-329

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Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner

24 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Lymphocyte signalling: a coordinating role for Vav?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Regulation of antigen receptor signal transduction by protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Translocation and clustering of endosomes and lysosomes depends on microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Polarity of T cell shape, motility, and sensitivity to antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Actin dynamics in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

The role of membrane-associated adaptors in T cell receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Essential role of LAT in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

How WASP regulates actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900112-1

7 January 2021

10.1016/S1074-7613(01)00112-1

Identifiers

DOI

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24 November 2017

1 reference