Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice (Q43534834)

24 November 2017

Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice (English)

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24 November 2017

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Mathieu Latreille

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author name string

Marie-Kristine Laberge

2

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24 November 2017

Geneviève Bourret

3

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24 November 2017

Lama Yamani

4

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24 November 2017

Louise Larose

5

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24 November 2017

29 June 2010

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American Journal of Physiology - Endocrinology and Metabolism

24 November 2017

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24 November 2017

300

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24 November 2017

3

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24 November 2017

E423-34

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Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance

24 November 2017

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https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Compensatory alterations for insulin signal transduction and glucose transport in insulin-resistant diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Socs1 deficiency enhances hepatic insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Modulation of protein translation by Nck-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

JAB1 participates in unfolded protein responses by association and dissociation with IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Localization of human ARF2 and NCK genes and 13 other NotI-linking clones to chromosome 3 by fluorescence in situ hybridization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

Direct monitoring of in vivo ER stress during the development of insulin resistance with ER stress-activated indicator transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00088.2010

10.1152/AJPENDO.00088.2010

21 January 2018

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release_kahyey4ymndbfbp4nlgrgu6oqq

24 November 2017

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