Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis (Q43454997)

23 November 2017

Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis (English)

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23 November 2017

4

Zeger Debyser

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Frauke Christ

series ordinal

2

object named as

Frauke Christ

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23 November 2017

Laith Q Al-Mawsawi

1

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23 November 2017

Raveendra Dayam

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3

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23 November 2017

Nouri Neamati

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5

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23 November 2017

language of work or name

English

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publication date

10 March 2008

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23 November 2017

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23 November 2017

582

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23 November 2017

10

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23 November 2017

1425-1430

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Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

23 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Cellular co-factors of HIV-1 integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

LEDGF, a survival factor, activates stress-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

An essential role for LEDGF/p75 in HIV integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

A role for LEDGF/p75 in targeting HIV DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Functional oligomeric state of avian sarcoma virus integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Discovery of a small-molecule HIV-1 integrase inhibitor-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

Loop202-208 in avian sarcoma virus integrase mediates tetramer assembly and processing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.02.076

10.1016/J.FEBSLET.2008.02.076

21 January 2018

Identifiers

DOI

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23 November 2017

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