Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. (Q43273391)

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scientific article published on 21 September 2009

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English	Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.	scientific article published on 21 September 2009

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8 February 2020

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells (English)

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8 February 2020

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Francisco Campos

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8 February 2020

Iolanda Vendrell

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Jordi Berenguer

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Mercedes Barzi

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8 February 2020

Cristina Suñol

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publication date

21 September 2009

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Toxicological Sciences

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112

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416-426

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2

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8 February 2020

Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction?

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

The Toxicology of Mercury — Current Exposures and Clinical Manifestations

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Catalase and glutathione peroxidase mimics

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

1 reference

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21 January 2018

Mercury compounds disrupt neuronal glutamate transport in cultured mouse cerebellar granule cells.

1 reference

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21 January 2018

Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels

1 reference

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21 January 2018

Developmental neurotoxicity of industrial chemicals

1 reference

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21 January 2018

Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfusion in the rat: correlation with the cytotoxic potential of H2O2 in vitro

1 reference

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21 January 2018

Inactivation of lactate dehydrogenase by several chemicals: implications for in vitro toxicology studies

1 reference

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21 January 2018

Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes.

1 reference

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21 January 2018

Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity.

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Comparative study of activities in reactive oxygen species production/defense system in mitochondria of rat brain and liver, and their susceptibility to methylmercury toxicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Transforming growth factor-alpha attenuates N-methyl-D-aspartic acid toxicity in cortical cultures by preventing protein synthesis inhibition through an Erk1/2-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

The mechanism for hexachlorocyclohexane-induced cytotoxicity and changes in intracellular Ca2+ homeostasis in cultured cerebellar granule neurons is different for the gamma- and delta-isomers.

1 reference

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21 January 2018

Peroxisomal proliferation protects from beta-amyloid neurodegeneration

1 reference

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21 January 2018

Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: specific induction of enzyme expression in reactive astrocytes following brain injury.

1 reference

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21 January 2018

Postnatal methylmercury exposure induces hyperlocomotor activity and cerebellar oxidative stress in mice: dependence on the neurodevelopmental period.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Selenium protection against mercury toxicity: high binding affinity of methylmercury by selenium-containing ligands in comparison with sulfur-containing ligands

1 reference

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21 January 2018

Cell viability and proteomic analysis in cultured neurons exposed to methylmercury

1 reference

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21 January 2018

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

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21 January 2018

Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP219

21 January 2018

Identifiers

10.1093/TOXSCI/KFP219

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19770487%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19770487%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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