Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain. (Q34202926)

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English	Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.	scientific article

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27 December 2019

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain (English)

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Jeferson Luis Franco

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Solange Cristina Garcia

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Alcir Luiz Dafré

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Joao Batista da Rocha

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Michael Aschner

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Michael Aschner

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Dejan Milatovic

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Dejan Milatovic

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Diogo O Souza

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Denise Bohrer

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James Stringari

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Adriana K C Nunes

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22 October 2007

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Toxicology and Applied Pharmacology

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1

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27 December 2019

Electrophilic cyclopentenone isoprostanes in neurodegeneration

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Cell viability and proteomic analysis in cultured neurons exposed to methylmercury

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Neurobehavioural and molecular changes induced by methylmercury exposure during development

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Methylmercury toxicity and functional programming

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Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.

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Lactational exposure to inorganic mercury: evidence of neurotoxic effects.

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Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes.

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Gestational exposure to methylmercury and selenium: effects on a spatial discrimination reversal in adulthood

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Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from the Seychelles Child Development Study

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Prenatal methylmercury exposure and developmental outcomes: review of the evidence and discussion of future directions

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Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells

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5 July 2018

Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes

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Peroxide detoxification by brain cells.

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Developmental neuropathology of environmental agents.

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5 July 2018

The Toxicology of Mercury — Current Exposures and Clinical Manifestations

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Low level methylmercury exposure affects neuropsychological function in adults

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Glutathione pathways in the brain.

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Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen

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5 July 2018

Methods and rationale for derivation of a reference dose for methylmercury by the U.S. EPA.

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Methylmercury alters glutamate transport in astrocytes

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Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury

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Multiple roles of glutathione in the central nervous system.

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Fixed interval/fixed ratio performance in adult monkeys exposed in utero to methylmercury.

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The toxicity, distribution and elimination of methylmercury in mice following intracerebral injection.

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Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

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Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohort.

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28 October 2018

SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.

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28 October 2018

Postnatal methylmercury exposure induces hyperlocomotor activity and cerebellar oxidative stress in mice: dependence on the neurodevelopmental period.

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28 October 2018

Cerebellar thiol status and motor deficit after lactational exposure to methylmercury.

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Protective effects of Polygala paniculata extract against methylmercury-induced neurotoxicity in mice

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28 October 2018

Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction?

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Perinatal and lifetime exposure to methylmercury in the mouse: behavioral effects.

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Effects of methylmercury on neurodevelopment in Japanese children in relation to the Madeiran study.

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Hippocampal antioxidant system in neonates from methylmercury-intoxicated rats

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28 October 2018

Maternal milk as methylmercury source for suckling mice: neurotoxic effects involved with the cerebellar glutamatergic system.

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28 October 2018

Delayed brainstem auditory evoked potential latencies in 14-year-old children exposed to methylmercury.

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28 October 2018

Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

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28 October 2018

Mechanisms of the inhibitory effects of selenium and mercury on the activity of delta-aminolevulinate dehydratase from mouse liver, kidney and brain.

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28 October 2018

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28 October 2018

Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase

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28 October 2018

Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons

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Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress

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12 December 2020

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Quantification of F2-isoprostanes as a biomarker of oxidative stress

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Methylmercury affects multiple subtypes of calcium channels in rat cerebellar granule cells

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Methyl mercuric chloride toxicokinetics in mice. I: Effects of strain, sex, route of administration and dose

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Glutathione peroxidase

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Transport of the glutathione-methylmercury complex across liver canalicular membranes on reduced glutathione carriers

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[Selenium in peroxide metabolism]

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12 December 2020

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Glutathione reductase

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Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice

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10.1016/J.TAAP.2007.10.010

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27 December 2019

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27 December 2019

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27 December 2019

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