PISA, a novel pharmacodynamic assay for assessing poly(ADP-ribose) polymerase (PARP) activity in situ (Q43173101)

15 November 2017

PISA, a novel pharmacodynamic assay for assessing poly(ADP-ribose) polymerase (PARP) activity in situ (English)

1 reference

15 November 2017

1 reference

Laura S Lubbers

1

1 reference

15 November 2017

Blake A Rowe

2

1 reference

15 November 2017

Lisa M Hodge

3

1 reference

15 November 2017

Susan E Browne

4

1 reference

15 November 2017

Richard Gundersdorf

5

1 reference

15 November 2017

Philip Jones

6

1 reference

15 November 2017

Fred J Hess

7

1 reference

15 November 2017

Ian J Reynolds

8

1 reference

15 November 2017

2 February 2010

1 reference

Journal of Pharmacological and Toxicological Methods

15 November 2017

1 reference

15 November 2017

61

1 reference

15 November 2017

319-328

1 reference

15 November 2017

3

1 reference

Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation.

15 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Synthesis of 11C-labelled benzamide compounds as potential tracers for poly(ADP-ribose) synthetase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Characterization and comparison of poly(adenosine diphosphoribose) synthesis and DNA synthesis in nucleotide-permeable cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Proliferative activity and nestin expression in periventricular cells of the adult rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Effects of kainic acid lesioning on poly(ADP-ribose) polymerase (PARP) activity in the rat striatum in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

In situ staining for poly(ADP-ribose) polymerase activity using an NAD analogue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A(2) inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

The role of poly(ADP-ribose) polymerase-1 in CNS disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Neuronal accumulation of poly(ADP-ribose) after brain ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Neuronal death in brain infarcts in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Effect of transient focal ischemia of mouse brain on energy state and NAD levels: no evidence that NAD depletion plays a major role in secondary disturbances of energy metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Poly(ADP-ribose): novel functions for an old molecule

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

The expression of PARP, NF-kappa B and parvalbumin is increased in Parkinson disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Novel modulators of poly(ADP-ribose) polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

Properties of poly(ADP-ribose) synthetase from rat pancreas and poly(ADP-ribosylation) of basic nuclear proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.012

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VASCN.2010.01.012

1 reference

15 November 2017

1 reference