DNA double-strand breaks: prior to but not sufficient in targeting hypermutation (Q42944715)

11 November 2017

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation (English)

1 reference

11 November 2017

5

1 reference

11 November 2017

4

Tasuku Honjo

0 references

Masamichi Muramatsu

series ordinal

2

object named as

Masamichi Muramatsu

1 reference

11 November 2017

Linda Bross

1

1 reference

PMCID

2193713

11 November 2017

Kazuo Kinoshita

series ordinal

3

1 reference

PMCID

2193713

11 November 2017

language of work or name

English

0 references

publication date

1 May 2002

1 reference

Journal of Experimental Medicine

11 November 2017

1 reference

11 November 2017

195

1 reference

11 November 2017

1187-1192

1 reference

11 November 2017

9

1 reference

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

DNA breaks in hypermutating immunoglobulin genes: evidence for a break-and-repair pathway of somatic hypermutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Towards an understanding of somatic hypermutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Transcription, beta-like DNA polymerases and hypermutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

In vivo and in vitro studies of immunoglobulin gene somatic hypermutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Error-prone candidates vie for somatic mutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Hypermutation targets a green fluorescent protein-encoding transgene in the presence of immunoglobulin enhancers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Somatic hypermutation of immunoglobulin genes is linked to transcription.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Clonal selection and learning in the antibody system

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

27 May 2018

Somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Somatic hypermutation in the heavy chain locus correlates with transcription.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Somatic hypermutation in mouse lambda chains.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

Transcription complex stability and chromatin dynamics in vivo.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193713

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

16 August 2018

2 references

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20011749

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/11994423

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Origin of Antibody Variation

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20011749

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11994423

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Strand breaks in immunoglobulin gene hypermutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11994423

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20011749

1 reference

11 November 2017

1 reference

11 November 2017

1 reference

PMCID

2193713