Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. (Q42801422)

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4 November 2019

title

Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay (English)

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4 November 2019

3

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4 November 2019

author name string

Suk W Park

1

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4 November 2019

Noureddine Lomri

2

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4 November 2019

John P Fruehauf

4

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4 November 2019

Eugene Mechetner

5

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4 November 2019

publication date

1 June 2003

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4 November 2019

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4 November 2019

volume

53

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4 November 2019

issue

2

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4 November 2019

page(s)

67-78

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Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues

4 November 2019

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Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

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The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2

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P-Glycoprotein conformational changes detected by antibody competition

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The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

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