Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation (Q42797749)

7 November 2017

Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation (English)

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7 November 2017

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Po-Chao Chan

1

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7 November 2017

Yen-Ling Chen

2

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7 November 2017

Chi-Hung Cheng

3

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7 November 2017

Kuo-Ching Yu

4

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7 November 2017

Leslie A Cary

5

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7 November 2017

Kuo-Hsiung Shu

6

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7 November 2017

William L Ho

7

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7 November 2017

Hong-Chen Chen

8

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7 November 2017

language of work or name

English

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publication date

25 August 2003

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

278

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7 November 2017

45

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7 November 2017

44075-44082

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The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis

7 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M305745200

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Scatter factor/hepatocyte growth factor is essential for liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305745200

Scatter factor induces blood vessel formation in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305745200

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Tyrosine kinase receptor indistinguishable from the c-met protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305745200

The "Gab" in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

SHP2 associates directly with tyrosine phosphorylated p90 (SNT) protein in FGF-stimulated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Essential role of Gab1 for signaling by the c-Met receptor in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

Epidermal Growth Factor-induced DNA Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305745200

21 January 2018

Identifiers

DOI

10.1074/JBC.M305745200

1 reference

7 November 2017

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