A review of genome-wide transcriptomics studies in Parkinson's disease (Q42778276)

7 November 2017

A review of genome-wide transcriptomics studies in Parkinson's disease (English)

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7 November 2017

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Soraya Seedat

3

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Helena Kuivaniemi

object named as

Helena Kuivaniemi

series ordinal

4

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Soraya Bardien

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5

object named as

Soraya Bardien

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7 November 2017

Genevie Borrageiro

1

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7 November 2017

William Haylett

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2

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7 November 2017

language of work or name

English

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publication date

25 October 2017

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European Journal of Neuroscience

7 November 2017

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Involvement of endocytosis and alternative splicing in the formation of the pathological process in the early stages of Parkinson's disease.

7 November 2017

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 January 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death

21 January 2018

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Brain transcriptomic profiling in idiopathic and LRRK2-associated Parkinson's disease.

21 January 2018

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Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease.

21 January 2018

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Identification of blood serum micro-RNAs associated with idiopathic and LRRK2 Parkinson's disease

21 January 2018

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Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

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Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

21 January 2018

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Midbrain dopamine neurons in Parkinson's disease exhibit a dysregulated miRNA and target-gene network

21 January 2018

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Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology

21 January 2018

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Blood transcriptomics of drug-naïve sporadic Parkinson's disease patients

21 January 2018

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Effects of gender on nigral gene expression and parkinson disease

21 January 2018

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MiRNA profile in the substantia nigra of Parkinson's disease and healthy subjects.

21 January 2018

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A network view on Parkinson's disease

21 January 2018

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Studying the system-level involvement of microRNAs in Parkinson's disease

21 January 2018

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Comparative analysis of RNA-Seq data from brain and blood samples of Parkinson's disease

21 January 2018

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Gene expression profiling in human neurodegenerative disease

21 January 2018

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Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigra

21 January 2018

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RNA-Seq and human complex diseases: recent accomplishments and future perspectives.

21 January 2018

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Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization.

21 January 2018

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Parkinson's disease: mechanisms and models

21 January 2018

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Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

21 January 2018

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The identification of dysfunctional crosstalk of pathways in Parkinson disease.

21 January 2018

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Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson's Disease.

21 January 2018

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A panel of four decreased serum microRNAs as a novel biomarker for early Parkinson's disease.

21 January 2018

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Identification of therapeutic targets for Parkinson's disease via bioinformatics analysis

21 January 2018

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Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153

21 January 2018

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Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.

21 January 2018

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Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation

21 January 2018

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Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease

21 January 2018

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A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity

21 January 2018

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Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach

21 January 2018

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Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

21 January 2018

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Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death.

21 January 2018

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Systematic analysis of microarray datasets to identify Parkinson's disease‑associated pathways and genes

21 January 2018

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Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease

21 January 2018

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Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson disease: novel putative chemoreceptors in the human brain.

21 January 2018

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Mitochondrial dysfunctions in Parkinson's disease

21 January 2018

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Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease

21 January 2018

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Current status and future directions of gene expression profiling in Parkinson's disease

21 January 2018

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Deregulation of α-synuclein in Parkinson's disease: Insight from epigenetic structure and transcriptional regulation of SNCA.

21 January 2018

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Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

21 January 2018

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Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism.

21 January 2018

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Is Parkinson's disease a primary olfactory disorder?

21 January 2018

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Next-generation profiling to identify the molecular etiology of Parkinson dementia

21 January 2018

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microRNA Profiles in Parkinson's Disease Prefrontal Cortex

21 January 2018

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Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson's Disease

21 January 2018

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How well do we recognise non-motor symptoms in a British Parkinson's disease population?

21 January 2018

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Identification of candidate genes for Parkinson's disease through blood transcriptome analysis in LRRK2-G2019S carriers, idiopathic cases, and controls

21 January 2018

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Comparative blood transcriptome analysis in idiopathic and LRRK2 G2019S-associated Parkinson's disease

21 January 2018

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Pathway analysis of the human brain transcriptome in disease

21 January 2018

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Decreased expression of B cell related genes in leukocytes of women with Parkinson's disease

21 January 2018

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miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.

21 January 2018

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Genetics of Parkinson's disease

21 January 2018

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Epidemiology of Parkinson's disease

21 January 2018

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Apoptosis and Parkinson's disease

21 January 2018

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Polyamine pathway contributes to the pathogenesis of Parkinson disease

21 January 2018

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Monte Carlo cross-validation analysis screens pathway cross-talk associated with Parkinson's disease

21 January 2018

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Microarray analysis of transcriptome of medulla identifies potential biomarkers for Parkinson's disease

21 January 2018

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Genetics of Parkinson's disease.

21 January 2018

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Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

21 January 2018

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Gene expression profiling predicts pathways and genes associated with Parkinson's disease

21 January 2018

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Meta-Analysis of Parkinson's Disease Transcriptome Data Using TRAM Software: Whole Substantia Nigra Tissue and Single Dopamine Neuron Differential Gene Expression.

21 January 2018

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Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease

21 January 2018

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Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?

21 January 2018

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Robust dysregulation of gene expression in substantia nigra and striatum in Parkinson's disease

21 January 2018

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MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

21 January 2018

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Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.

21 January 2018

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Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation

21 January 2018

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Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease.

21 January 2018

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Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation

21 January 2018

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Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease

21 January 2018

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Alterations of miRNAs reveal a dysregulated molecular regulatory network in Parkinson's disease striatum.

21 January 2018

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Parkin-induced mitophagy in the pathogenesis of Parkinson disease

21 January 2018

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Mitochondrial abnormalities in the putamen in Parkinson's disease dyskinesia

21 January 2018

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RNA-binding disturbances as a continuum from spinocerebellar ataxia type 2 to Parkinson disease

21 January 2018

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Multiregional gene expression profiling identifies MRPS6 as a possible candidate gene for Parkinson's disease.

21 January 2018

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Synaptic dysfunction in Parkinson's disease.

21 January 2018

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Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles

21 January 2018

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Looking beyond the brain to improve the pathogenic understanding of Parkinson's disease: implications of whole transcriptome profiling of Patients' skin.

21 January 2018

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Biosignatures for Parkinson's disease and atypical parkinsonian disorders patients

21 January 2018

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Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease

21 January 2018

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Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms

21 January 2018

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Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson's disease

21 January 2018

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Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

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Molecular markers of early Parkinson's disease based on gene expression in blood

21 January 2018

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SRRM2, a potential blood biomarker revealing high alternative splicing in Parkinson's disease

21 January 2018

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Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

21 January 2018

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Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

21 January 2018

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Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease

21 January 2018

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Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients

21 January 2018

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Deep brain stimulation induces rapidly reversible transcript changes in Parkinson's leucocytes

21 January 2018

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Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes

21 January 2018

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Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson's patients leukocytes

21 January 2018

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Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes

21 January 2018

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Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing

21 January 2018

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Genetic susceptibility variants in parkinsonism

21 January 2018

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Alpha-synuclein in Lewy bodies

21 January 2018

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Neuronal gene expression correlates of Parkinson's disease with dementia

21 January 2018

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Identification of potential drugs for Parkinson's disease based on a sub-pathway method

21 January 2018

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A cross-study transcriptional analysis of Parkinson's disease

21 January 2018

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RNA-Seq analysis to capture the transcriptome landscape of a single cell

21 January 2018

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Identification of circulating microRNAs for the differential diagnosis of Parkinson's disease and Multiple System Atrophy.

21 January 2018

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miRNAs as biomarkers of neurodegenerative disorders

21 January 2018

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Transcriptional changes in multiple system atrophy and Parkinson's disease putamen

21 January 2018

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Novel microRNA discovery using small RNA sequencing in post-mortem human brain.

21 January 2018

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Neuroinflammation in Parkinson's disease and its potential as therapeutic target

21 January 2018

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Meta-Analysis of Parkinson's Disease and Alzheimer's Disease Revealed Commonly Impaired Pathways and Dysregulation of NRF2-Dependent Genes.

21 January 2018

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Progression of motor symptoms in Parkinson's disease

21 January 2018

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Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms.

21 January 2018

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Identification of key pathways and transcription factors related to Parkinson disease in genome wide

21 January 2018

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PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

21 January 2018

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Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/EJN.13760

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release_v4nke52ryngo3ke6wengtuk52a

7 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/v4nke52ryngo3ke6wengtuk52a

mapped directly with Wikidata item

24 November 2022

based on heuristic

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