Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice. (Q42720829)

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24 January 2020

title

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice (English)

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24 January 2020

7

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Kevin Croft

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24 January 2020

author name string

Roheeth D Delima

1

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24 January 2020

Anita C G Chua

2

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24 January 2020

Janina E E Tirnitz-Parker

3

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24 January 2020

Eng K Gan

4

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24 January 2020

Ross M Graham

6

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24 January 2020

Debbie Trinder

8

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language of work or name

English

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publication date

11 June 2012

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24 January 2020

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24 January 2020

volume

56

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issue

2

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24 January 2020

page(s)

585-593

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Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment

24 January 2020

cites work

1 reference

A population-based study of the clinical expression of the hemochromatosis gene

21 January 2018

1 reference

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

1 reference

Iron-overload-related disease in HFE hereditary hemochromatosis

21 January 2018

1 reference

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 January 2018

1 reference

Hereditary hemochromatosis in the post-HFE era

21 January 2018

1 reference

Hepatic stellate cell activation in genetic haemochromatosis. Lobular distribution, effect of increasing hepatic iron and response to phlebotomy.

21 January 2018

1 reference

Enhanced γ-Glutamyl Transpeptidase Expression and Selective Loss of CuZn Superoxide Dismutase in Hepatic Iron Overload

21 January 2018

1 reference

Elevated F2-isoprostanes in thalassemic patients

21 January 2018

1 reference

Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives

21 January 2018

1 reference

Function of the hemochromatosis protein HFE: Lessons from animal models

21 January 2018

1 reference

HFE gene knockout produces mouse model of hereditary hemochromatosis

21 January 2018

1 reference

Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

21 January 2018

1 reference

Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

21 January 2018

1 reference

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 January 2018

1 reference

Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe

21 January 2018

1 reference

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells

21 January 2018

1 reference

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

21 January 2018

1 reference

In silico QTL mapping of basal liver iron levels in inbred mouse strains

21 January 2018

1 reference

Mitochondrial damage, cytotoxicity and apoptosis in iron-potentiated alcoholic liver fibrosis: amelioration by taurine

21 January 2018

1 reference

The importance of non-transferrin bound iron in disorders of iron metabolism

21 January 2018

1 reference

HFE genotype in patients with hemochromatosis and other liver diseases.

21 January 2018

1 reference

Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.

21 January 2018

1 reference

Pathology of hepatic iron overload

21 January 2018

1 reference

Clinical and pathologic findings in hemochromatosis type 3 due to a novel mutation in transferrin receptor 2 gene

21 January 2018

1 reference

7 January 2021

Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene

1 reference

7 January 2021

Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis?

1 reference

7 January 2021

Formation of 1,N6-ethenoadenine and 3,N4-ethenocytosine by lipid peroxidation products and nucleic acid bases

1 reference

7 January 2021

1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabeling

1 reference

7 January 2021

Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis

1 reference

7 January 2021

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

1 reference

7 January 2021

Studies on intermediary iron metabolism. V. The measurement of non-haemoglobin tissue iron

1 reference

7 January 2021

An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry

1 reference

7 January 2021

Pathophysiology of iron toxicity.

1 reference

7 January 2021

Liver gene expression during chronic dietary iron overload in rats

1 reference

7 January 2021

Iron overload facilitates hepatic fibrosis in the rat alcohol/low-dose carbon tetrachloride model

1 reference

7 January 2021

Biochemical liver profile in hemochromatosis. A survey of 100 patients

1 reference

7 January 2021

Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations

1 reference

7 January 2021

Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis

1 reference

7 January 2021