Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis (Q33894300)

29 July 2017

title

Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis (English)

1 reference

29 July 2017

John K Olynyk

10

1 reference

ORCID Public Data File 2021

author name string

Anita C G Chua

1

1 reference

29 July 2017

Roheeth D Delima

2

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29 July 2017

Evan H Morgan

3

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29 July 2017

Carly E Herbison

4

1 reference

29 July 2017

Janina E E Tirnitz-Parker

5

1 reference

29 July 2017

Ross M Graham

6

1 reference

29 July 2017

Robert E Fleming

7

1 reference

29 July 2017

Robert S Britton

8

1 reference

29 July 2017

Bruce R Bacon

9

1 reference

29 July 2017

Debbie Trinder

11

1 reference

29 July 2017

publication date

6 January 2010

1 reference

29 July 2017

published in

Journal of Hepatology

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29 July 2017

volume

52

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29 July 2017

issue

3

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29 July 2017

page(s)

425-431

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Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Diferric transferrin regulates transferrin receptor 2 protein stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Regulation of transferrin receptor 2 protein levels by transferrin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Transferrin receptor 2 protein is not expressed in normal erythroid cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

The role of Hfe in transferrin-bound iron uptake by hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Iron regulation and erythropoiesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Transferrin receptor 2 mediates uptake of transferrin-bound and non-transferrin-bound iron.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Limited iron export by hepatocytes contributes to hepatic iron-loading in the Hfe knockout mouse.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Hepcidin is decreased in TFR2 hemochromatosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880807

Decreased liver hepcidin expression in the Hfe knockout mouse

29 October 2018

1 reference

12 December 2020

Studies on intermediary iron metabolism. V. The measurement of non-haemoglobin tissue iron

1 reference

12 December 2020

Homozygous p.M172K mutation of the TFR2 gene in an Italian family with type 3 hereditary hemochromatosis and early onset iron overload

1 reference

12 December 2020

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

1 reference

12 December 2020

New TFR2 mutations in young Italian patients with hemochromatosis

1 reference

12 December 2020

Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

1 reference

12 December 2020

10.1016/J.JHEP.2009.12.010

Identifiers

DOI

1 reference

29 July 2017

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29 July 2017

1 reference