Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors. (Q42594382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24969632%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors (English)

1 reference

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21 March 2020

1 reference

1

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21 March 2020

Sylvain Houle

4

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21 March 2020

author name string

Jun Parkes

2

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21 March 2020

Junchao Tong

3

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21 March 2020

Neil Vasdev

5

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21 March 2020

Alan A Wilson

6

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21 March 2020

publication date

10 May 2014

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Nuclear Medicine and Biology

21 March 2020

published in

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21 March 2020

volume

41

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21 March 2020

page(s)

688-694

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21 March 2020

issue

8

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Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase

21 March 2020

cites work

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Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.

28 May 2018

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Mapping human brain fatty acid amide hydrolase activity with PET.

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An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis

28 May 2018

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The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).

28 May 2018

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Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates

28 May 2018

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28 May 2018

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Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases

28 May 2018

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Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism

28 May 2018

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One-pot, direct incorporation of [11C]CO2 into carbamates

28 May 2018

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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

28 May 2018

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Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo

28 May 2018

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In vivo site-directed radiotracers: a mini-review

28 May 2018

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Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors

28 May 2018

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Fundamentals of positron emission tomography and applications in preclinical drug development

28 May 2018

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An admonition when measuring the lipophilicity of radiotracers using counting techniques

28 May 2018

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28 May 2018

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Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [(11)C-carbonyl] AR-A014418 by [(11)C]CO(2) fixation.

28 May 2018

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16 August 2018

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16 August 2018

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Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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In vivo studies of acetylcholinesterase activity using a labeled substrate, N-[11C]methylpiperdin-4-yl propionate ([11C]PMP).

16 August 2018

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Monoglyceride hydrolase activities of rat plasma and platelets. Their properties and roles in the activity of lipoprotein lipase

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24969632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24969632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NUCMEDBIO.2014.05.001

1 reference

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21 March 2020

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21 March 2020

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