KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein (Q42520564)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908235%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein (English)

1 reference

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11 February 2020

3

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11 February 2020

Moshe Giladi

4

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11 February 2020

author name string

Eshcar Meisel

1

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11 February 2020

Meidan Dvir

2

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11 February 2020

Asher Peretz

5

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11 February 2020

Bernard Attali

6

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11 February 2020

language of work or name

English

0 references

publication date

20 August 2012

1 reference

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Journal of Biological Chemistry

11 February 2020

published in

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11 February 2020

volume

287

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11 February 2020

issue

41

1 reference

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11 February 2020

page(s)

34212-34224

1 reference

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Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels

11 February 2020

cites work

1 reference

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28 May 2018

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Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis

28 May 2018

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KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

28 May 2018

1 reference

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KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function

28 May 2018

1 reference

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The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers

28 May 2018

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Stoichiometry of the KCNQ1 - KCNE1 ion channel complex.

28 May 2018

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R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation

28 May 2018

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Intracellular domains interactions and gated motions of I(KS) potassium channel subunits

28 May 2018

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A single charged voltage sensor is capable of gating the Shaker K+ channel

28 May 2018

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Direct analysis of cooperativity in multisubunit allosteric proteins

28 May 2018

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Tethering chemistry and K+ channels

28 May 2018

1 reference

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Gating consequences of charge neutralization of arginine residues in the S4 segment of K(v)7.2, an epilepsy-linked K+ channel subunit

28 May 2018

1 reference

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KCNE1 constrains the voltage sensor of Kv7.1 K+ channels

28 May 2018

1 reference

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Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications

28 May 2018

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The C-terminus of Kv7 channels: a multifunctional module.

28 May 2018

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Kv7.1 (KCNQ1) properties and channelopathies.

28 May 2018

1 reference

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The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction

28 May 2018

1 reference

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Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel

28 May 2018

1 reference

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The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes

28 May 2018

1 reference

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Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

28 May 2018

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The cooperative voltage sensor motion that gates a potassium channel

28 May 2018

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A quantitative description of membrane current and its application to conduction and excitation in nerve

28 May 2018

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The voltage-gated potassium channels and their relatives

28 May 2018

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KCNE regulation of KvLQT1 channels: structure-function correlates

28 May 2018

1 reference

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KCNQ potassium channels: physiology, pathophysiology, and pharmacology

28 May 2018

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Neuronal KCNQ potassium channels: physiology and role in disease.

28 May 2018

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Immobilizing the moving parts of voltage-gated ion channels

28 May 2018

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A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs).

28 May 2018

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Long QT syndrome-associated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits.

28 May 2018

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Mutations in a dominant-negative isoform correlate with phenotype in inherited cardiac arrhythmias

28 May 2018

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Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

28 May 2018

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Single-channel properties of IKs potassium channels

28 May 2018

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Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome

28 May 2018

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Genomic structure of three long QT syndrome genes: KVLQT1, HERG, and KCNE1.

28 May 2018

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Activation and inactivation of homomeric KvLQT1 potassium channels.

28 May 2018

1 reference

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Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits

28 May 2018

1 reference

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Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels

28 May 2018

1 reference

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How does the W434F mutation block current in Shaker potassium channels?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464529

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464529

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464529

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464529

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

28 May 2018

1 reference

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Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethylammonium

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464529

Evidence for cooperative interactions in potassium channel gating

28 May 2018

1 reference

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Gating currents from neuronal K(V)7.4 channels: general features and correlation with the ionic conductance.

28 May 2018

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Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations.

16 August 2018

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Voltage sensor of Kv1.2: structural basis of electromechanical coupling

16 August 2018

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Subunit composition of minK potassium channels.

16 August 2018

1 reference

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Energetics of pore opening in a voltage-gated K(+) channel

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22908235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22908235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22908235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.364901

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908235%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908235%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference