Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels (Q35935730)

11 August 2017

Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels (English)

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11 August 2017

Jeremiah D Osteen

1

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11 August 2017

Rene Barro-Soria

2

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11 August 2017

Seth Robey

3

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11 August 2017

Kevin J Sampson

4

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11 August 2017

Robert S Kass

5

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11 August 2017

H Peter Larsson

6

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11 August 2017

language of work or name

English

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publication date

16 April 2012

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

6

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based on heuristic

inferred from page(s)

published in

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11 August 2017

109

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11 August 2017

7103-7108

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11 August 2017

18

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Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Ion channel voltage sensors: structure, function, and pathophysiology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Voltage-gated potassium channels: regulation by accessory subunits

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

The KCNQ1 potassium channel: from gene to physiological function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Molecular physiology of cardiac repolarization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

The MinK-related peptides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

A quantitative description of membrane current and its application to conduction and excitation in nerve

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

A constitutively open potassium channel formed by KCNQ1 and KCNE3

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Allosteric voltage gating of potassium channels II. Mslo channel gating charge movement in the absence of Ca(2+).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Shaker potassium channel gating. II: Transitions in the activation pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Long QT syndrome: from channels to cardiac arrhythmias

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Integrated allosteric model of voltage gating of HCN channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344993

24 September 2018

Identifiers

DOI

10.1073/PNAS.1201582109

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11 August 2017

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11 August 2017

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