RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer (Q42505152)

http://europepmc.org/abstract/PMC/5384017

10 June 2018

title

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer (English)

1 reference

http://europepmc.org/abstract/PMC/5384017

10 June 2018

1 reference

2

1 reference

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11 June 2020

Vassilis Gorgoulis

8

1 reference

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11 June 2020

eli pikarsky

9

1 reference

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11 June 2020

Moshe Oren

11

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11 June 2020

author name string

Ohad Tarcic

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28157208%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ioannis S Pateras

3

1 reference

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11 June 2020

Hadas Masury

4

1 reference

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11 June 2020

Bella Maly

5

1 reference

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11 June 2020

Yaara Zwang

6

1 reference

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11 June 2020

Yosef Yarden

7

1 reference

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11 June 2020

Ittai Ben-Porath

10

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11 June 2020

publication date

3 February 2017

1 reference

http://europepmc.org/abstract/PMC/5384017

10 June 2018

published in

Cell Death & Differentiation

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11 June 2020

volume

24

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11 June 2020

issue

4

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11 June 2020

page(s)

694-704

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28157208%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cdd.2016.126

11 June 2020

exact match

0 references

cites work

Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.

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RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

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14 June 2018

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14 June 2018

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14 June 2018

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NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype

14 June 2018

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The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).

14 June 2018

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Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.

14 June 2018

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14 June 2018

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Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

14 June 2018

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Molecular characterization of basal-like and non-basal-like triple-negative breast cancer

14 June 2018

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The genomic landscape of breast cancer as a therapeutic roadmap

14 June 2018

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Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion

14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability

14 June 2018

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14 June 2018

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Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B.

14 June 2018

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Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals

14 June 2018

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14 June 2018

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Deconstructing the molecular portraits of breast cancer

14 June 2018

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Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

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14 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Supervised risk predictor of breast cancer based on intrinsic subtypes

14 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Patho-biological aspects of basal-like breast cancer

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Regulation of histone H2A and H2B ubiquitylation

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Dual-color-coded imaging of viable circulating prostate carcinoma cells reveals genetic exchange between tumor cells in vivo, contributing to highly metastatic phenotypes

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5384017

16 August 2018

Identifiers

DOI

10.1038/CDD.2016.126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28157208%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28157208%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference