The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. (Q50336173)

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scientific article published on 21 October 2011

Language	Label	Description	Also known as
English	The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.	scientific article published on 21 October 2011

Statements

scholarly article

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. (English)

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

author name string

Michael A Hahn

1

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Kristie-Ann Dickson

2

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Stuart Jackson

3

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Adele Clarkson

4

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Anthony J Gill

5

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Deborah J Marsh

6

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

publication date

21 October 2011

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Human Molecular Genetics

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Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

21

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Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

3

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

559-568

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The parafibromin tumor suppressor protein is part of a human Paf1 complex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The Paf1 complex: platform or player in RNA polymerase II transcription?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Human RNA polymerase II-associated factor complex: dysregulation in cancer.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Loss of parafibromin immunoreactivity is a distinguishing feature of parathyroid carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Nucleolar localization of parafibromin is mediated by three nucleolar localization signals

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Defective nucleolar localization and dominant interfering properties of a parafibromin L95P missense mutant causing the hyperparathyroidism-jaw tumor syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Somatic and Germ-Line Mutations of theHRPT2Gene in Sporadic Parathyroid Carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Hyperparathyroidism-jaw tumour syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Hyperparathyroid and hypoparathyroid disorders

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Parafibromin expression in breast cancer: a novel marker for prognostication?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Downregulated parafibromin expression is a promising marker for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Parafibromin expression is an independent prognostic factor for colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Histone H2B ubiquitination: the cancer connection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

The effect of disease-associated HRPT2 mutations on splicing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR490

21 January 2018

Identifiers

10.1093/HMG/DDR490

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/22021426

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