The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. (Q42500271)

1 November 2017

The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin (English)

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11 May 2020

7

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11 May 2020

David S Park

8

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11 May 2020

author name string

Yi Zhang

1

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11 May 2020

Dianbo Qu

2

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11 May 2020

Erick J Morris

3

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11 May 2020

Michael J O'Hare

4

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11 May 2020

Steven M Callaghan

5

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11 May 2020

Ruth S Slack

6

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11 May 2020

language of work or name

English

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publication date

1 August 2006

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1 November 2017

Journal of Neuroscience

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11 May 2020

volume

26

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issue

34

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11 May 2020

page(s)

8819-8828

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Optimization of single-cell gel electrophoresis (SCGE) for quantitative analysis of neuronal DNA damage.

11 May 2020

cites work

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12 December 2020

Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway

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12 December 2020

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

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12 December 2020

Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons.

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12 December 2020

Pathobiology of ischaemic stroke: an integrated view

1 reference

12 December 2020

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

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12 December 2020

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

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12 December 2020

Mitotic signaling by beta-amyloid causes neuronal death

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12 December 2020

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

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12 December 2020

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

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12 December 2020

Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain

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12 December 2020

Rapid destruction of human Cdc25A in response to DNA damage

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12 December 2020

Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

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12 December 2020

Induction and modulation of cerebellar granule neuron death by E2F-1

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12 December 2020

The transcription factor E2F1 modulates apoptosis of neurons

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12 December 2020

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

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12 December 2020

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

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12 December 2020

Cyclin-dependent kinases as a therapeutic target for stroke.

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12 December 2020

The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease

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12 December 2020

Regulation of the retinoblastoma-dependent Mdm2 and E2F-1 signaling pathways during neuronal apoptosis

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12 December 2020

Mechanism of action of camptothecin

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12 December 2020

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

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12 December 2020

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

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12 December 2020

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

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12 December 2020

Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease

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12 December 2020

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

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12 December 2020

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

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12 December 2020

Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors

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12 December 2020

Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

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12 December 2020

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

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12 December 2020

Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease.

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12 December 2020

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

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12 December 2020

Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.

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12 December 2020

The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons.

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12 December 2020

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

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12 December 2020

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

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12 December 2020

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

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12 December 2020

Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells

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12 December 2020

Screening for antimitotic compounds using the cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2/cyclin Bcdc13 protein kinase

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12 December 2020

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

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12 December 2020

Cell cycle molecules and vertebrate neuron death: E2F at the hub.

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12 December 2020

Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons

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12 December 2020

Erythromycin associated hearing loss in a patient with prior cis-platinum induced ototoxicity

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12 December 2020

Cell cycle activation linked to neuronal cell death initiated by DNA damage

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12 December 2020

Cell cycle regulation of neuronal apoptosis in development and disease.

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12 December 2020

Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.

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12 December 2020

CDKs: taking on a role as mediators of dopaminergic loss in Parkinson's disease.

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12 December 2020

Chk1 versus Cdc25: chking one's levels of cellular proliferation

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12 December 2020

Divide and die: cell cycle events as triggers of nerve cell death.

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12 December 2020

Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats

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12 December 2020

Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

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12 December 2020

Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo.

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12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

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12 December 2020

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

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12 December 2020

DNA damage and chronic neuronal degenerations

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12 December 2020

Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation

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12 December 2020

Induction and rejoining of radiation-induced DNA single-strand breaks: "tail moment" as a function of position in the cell cycle

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12 December 2020

Cognitive deficits in long-term survivors of childhood medulloblastoma and other noncortical tumors: age-dependent effects of whole brain radiation.

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12 December 2020

MR of cis-platinum-induced optic neuritis.

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12 December 2020

D-type cyclin-dependent kinase activity in mammalian cells

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12 December 2020

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

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12 December 2020

DNA single-strand breaks in postischemic gerbil brain detected by in situ nick translation procedure

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12 December 2020

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

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12 December 2020

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

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12 December 2020

Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.

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12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

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12 December 2020

Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.

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12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

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12 December 2020

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

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12 December 2020

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

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12 December 2020

Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death.

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12 December 2020

Apoptosis in neurodegenerative disorders

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12 December 2020

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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12 December 2020

Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

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12 December 2020

Immunoreactivity of cyclin D1/cdk4 in neurons and oligodendrocytes after focal cerebral ischemia in rat.

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12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

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12 December 2020

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

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12 December 2020

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

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12 December 2020

Oxidative mechanisms in nigral cell death in Parkinson's disease.

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12 December 2020

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

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12 December 2020

Increased nuclear DNA oxidation in the brain in Alzheimer's disease.

1 reference

12 December 2020

10.1523/JNEUROSCI.2593-06.2006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674376&resulttype=core&format=json

11 May 2020

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11 May 2020

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