Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species (Q42492733)

1 November 2017

Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species (English)

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1 November 2017

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reactive oxygen species

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Liou JS

1

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1 November 2017

Chen CY

series ordinal

2

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1 November 2017

Chen JS

series ordinal

3

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1 November 2017

Faller DV

series ordinal

4

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1 November 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

1 November 2017

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1 November 2017

275

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1 November 2017

39001-39011

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1 November 2017

50

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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Ras signalling and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Differential regulation of discrete apoptotic pathways by Ras.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Oncogenic Ras sensitizes cells to apoptosis by Par-4.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Suppression of Ras-induced apoptosis by the Rac GTPase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Protein kinase C involvement in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Role of redox potential and reactive oxygen species in stress signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Ras, superoxide and signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

P21 v-ras inhibits induction of c-myc and c-fos expression by platelet-derived growth factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Down-regulation of protein kinase C is due to an increased rate of degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Programmed cell death and Bcl-2 protection in very low oxygen.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Identification of a superoxide-generating NADPH oxidase system in human fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Mitochondria and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Mitochondrial control of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Accumulation of an alkyl lysophospholipid in tumor cell membranes affects membrane fluidity and tumor cell invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Ether lipids inhibit the effects of phorbol diester tumor promoters

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Hydrogen peroxide formation and DNA base modification by tumor promoter-activated polymorphonuclear leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Correlation of genetic instability and apoptosis in the presence of oncogenic Ki-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Reactive oxygen species and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Bi-transgenic mice reveal that K-rasVal12 augments a p53-independent apoptosis when small intestinal villus enterocytes reenter the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Apoptosis and the cell cycle.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Cell cycle regulation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Clinical implications of the p53 tumor-suppressor gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007154200

Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007154200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007154200

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1 November 2017

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