Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin (Q42484138)

1 November 2017

Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin (English)

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1 November 2017

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squamous cell carcinoma

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Qiao W

1

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1 November 2017

Li AG

2

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1 November 2017

Owens P

3

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1 November 2017

Xu X

4

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1 November 2017

Wang XJ

5

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1 November 2017

Deng CX

6

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1 November 2017

language of work or name

English

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publication date

1 January 2006

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1 November 2017

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1 November 2017

25

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1 November 2017

207-217

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1 November 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209029

1 November 2017

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cites work

Stem cells of the skin epithelium

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Expression of a dominant negative type II TGF-beta receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

At the roots of a never-ending cycle.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Roles of TGFbeta signaling in epidermal/appendage development

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

TGF-beta signal transduction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Regulation of Smad7 promoter by direct association with Smad3 and Smad4.

21 January 2018

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PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

21 January 2018

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The biology and clinical relevance of the PTEN tumor suppressor pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Delays in malignant tumor development in transgenic mice by forced epidermal keratin 10 expression in mouse skin carcinomas

21 January 2018

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Functional roles of Akt signaling in mouse skin tumorigenesis.

21 January 2018

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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

New insights into TGF-beta-Smad signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Cre-mediated gene deletion in the mammary gland

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

7 January 2021

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

7 January 2021

Orofacial and gastrointestinal hyperplasia and neoplasia in smad4+/- and elf+/-/smad4+/- mutant mice

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

7 January 2021

Controls of hair follicle cycling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

7 January 2021

Generation of Smad4/Dpc4 conditional knockout mice

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209029

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209029

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Dimensions Publication ID

1 November 2017

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