Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells (Q42459554)

1 November 2017

Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells (English)

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1 November 2017

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1 November 2017

Marcus Lundberg

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author name string

Santosh Kumar Boddeti

series ordinal

2

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PubMed ID

24865476

1 November 2017

Nils Welsh

series ordinal

4

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PubMed ID

24865476

1 November 2017

language of work or name

English

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publication date

1 January 2015

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1 November 2017

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1 November 2017

128

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1 November 2017

1

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1 November 2017

17-28

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 November 2017

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https://api.crossref.org/works/10.1042%2FCS20130560

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Potential of small molecule protein tyrosine kinase inhibitors as immuno-modulators and inhibitors of the development of type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib and regression of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Effects of Imatinib Mesylate (Gleevec) on human islet NF-kappaB activation and chemokine production in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

High glucose-induced upregulation of Rho/Rho-kinase via platelet-derived growth factor receptor-beta increases migration of aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Plasma adiponectin levels are markedly elevated in imatinib-treated chronic myeloid leukemia (CML) patients: a mechanism for improved insulin sensitivity in type 2 diabetic CML patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Glucose-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase-dependent upregulation of the platelet-derived growth factor-beta receptor potentiates vascular smooth muscle cell chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

LRP: role in vascular wall integrity and protection from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib attenuates diabetes-associated atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Modulation of β-cell function: a translational journey from the bench to the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

c-abl is involved in the association of p53 and trk A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Abl functions as a negative regulator of Met-induced cell motility via phosphorylation of the adapter protein CrkII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130560

21 January 2018

Identifiers

DOI

10.1042/CS20130560

1 reference

1 November 2017

1 reference

PubMed ID

24865476