TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway (Q42320459)

25 October 2017

TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway (English)

1 reference

25 October 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Zhouyi Rong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Xin Wang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Lin Jia

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Chia-Chen Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Li Zhong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Longyu Yang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Xiao-Fen Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

John D Fryer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Yun-Wu Zhang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Huaxi Xu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Guojun Bu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

11 January 2017

1 reference

25 October 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

1772-1784

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5320608/fullTextXML

inferred from PubMed Central ID database lookup

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TREM2 sustains microglial expansion during aging and response to demyelination

26 October 2017

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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

26 October 2017

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TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

26 October 2017

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TREM2 regulates microglial cell activation in response to demyelination in vivo

26 October 2017

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26 October 2017

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TREM-2 promotes macrophage-mediated eradication of Pseudomonas aeruginosa via a PI3K/Akt pathway

26 October 2017

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Genomic insights into WNT/β-catenin signaling

26 October 2017

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TREM2 and the neuroimmunology of Alzheimer's disease

26 October 2017

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The microglial sensome revealed by direct RNA sequencing

26 October 2017

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Glycogen synthase kinase 3 beta (GSK3β) at the tip of neuronal development and regeneration

26 October 2017

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TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway

26 October 2017

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Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation

26 October 2017

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Microglia regulate the number of neural precursor cells in the developing cerebral cortex

26 October 2017

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Microglia: scapegoat, saboteur, or something else?

26 October 2017

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Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

26 October 2017

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TREM2 Variants in Alzheimer's Disease

26 October 2017

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Variant of TREM2 Associated with the Risk of Alzheimer's Disease

26 October 2017

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26 October 2017

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26 October 2017

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TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis

26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via the PI3-kinase/Akt pathway in cultured Ra2 microglial cells

26 October 2017

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Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt.

26 October 2017

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The Wnt signaling pathway in development and disease

26 October 2017

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TREMs in the immune system and beyond

26 October 2017

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Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

26 October 2017

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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Microglial response to amyloid plaques in APPsw transgenic mice.

26 October 2017

1 reference

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beta-catenin is a target for the ubiquitin-proteasome pathway

26 October 2017

1 reference

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PI3K: downstream AKTion blocks apoptosis

26 October 2017

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

26 October 2017

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Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

29 May 2018

1 reference

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TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Targeting microglia for the treatment of Alzheimer's Disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Microglia modulate wiring of the embryonic forebrain.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5320608

TREM2 and Neurodegenerative Disease

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28077724

12 December 2020

inferred from PubMed ID database lookup

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28077724

12 December 2020

inferred from PubMed ID database lookup

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28077724

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.2459-16.2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077724%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference