Kainic acid-induced neurodegenerative model: potentials and limitations (Q34355569)

1 August 2017

5 references

25 April 2019

20 June 2019

17 September 2019

19 September 2019

3 December 2020

Kainic acid-induced neurodegenerative model: potentials and limitations (English)

1 reference

1 August 2017

4 references

25 April 2019

20 June 2019

17 September 2019

19 September 2019

heterocyclic compound

1 reference

biomedical investigative technique

17 September 2019

1 reference

19 September 2019

1 reference

3 December 2020

Xiang-Yu Zheng

1

1 reference

1 August 2017

Hong-Liang Zhang

series ordinal

2

1 reference

1 August 2017

Qi Luo

series ordinal

3

1 reference

1 August 2017

Jie Zhu

series ordinal

4

1 reference

1 August 2017

24 November 2010

6 references

Journal of Biomedicine and Biotechnology

1 August 2017

25 April 2019

20 June 2019

17 September 2019

19 September 2019

3 December 2020

6 references

1 August 2017

25 April 2019

20 June 2019

17 September 2019

19 September 2019

3 December 2020

2011

1 reference

1 August 2017

457079

1 reference

Creative Commons Attribution 3.0 Unported

1 August 2017

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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6 July 2018

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Kainic acid-mediated excitotoxicity as a model for neurodegeneration

6 July 2018

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6 July 2018

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Interleukin-18 stimulates synaptically released glutamate and enhances postsynaptic AMPA receptor responses in the CA1 region of mouse hippocampal slices

6 July 2018

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Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit

6 July 2018

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Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis

6 July 2018

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Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors

6 July 2018

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Inflammatory mechanisms associated with brain damage induced by kainic acid with special reference to the interleukin-1 system.

6 July 2018

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AMPA/kainate receptors in mouse spinal cord cell-specific display of receptor subunits by oligodendrocytes and astrocytes and at the nodes of Ranvier

6 July 2018

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Loss of kainate receptor-mediated heterosynaptic facilitation of mossy-fiber synapses in KA2-/- mice

6 July 2018

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Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

6 July 2018

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The two faces of IL-6 on Th1/Th2 differentiation

6 July 2018

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6 July 2018

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6 July 2018

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Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures

6 July 2018

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Arginine metabolism and the synthesis of nitric oxide in the nervous system

6 July 2018

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Nitric oxide as modulator of neuronal function

6 July 2018

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Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures.

6 July 2018

1 reference

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Cytokines in CNS disorders: neurotoxicity versus neuroprotection.

6 July 2018

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6 July 2018

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The initiation of the microglial response

6 July 2018

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AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro.

6 July 2018

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Differential distribution of ionotropic glutamate receptor subunits in the rat olfactory bulb

6 July 2018

1 reference

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Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

6 July 2018

1 reference

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Expression of non-N-methyl-D-aspartate glutamate receptor subunits in the olfactory epithelium.

6 July 2018

1 reference

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Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells.

6 July 2018

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Transforming growth factor-beta 1: a lesion-associated cytokine of the nervous system

6 July 2018

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Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

6 July 2018

1 reference

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Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein

6 July 2018

1 reference

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Mitochondrial dysfunction and ultrastructural damage in the hippocampus during kainic acid-induced status epilepticus in the rat.

6 July 2018

1 reference

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Behavioral alterations in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainate

21 January 2018

1 reference

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Post-treatment, but not pre-treatment, with the selective cyclooxygenase-2 inhibitor celecoxib markedly enhances functional recovery from kainic acid-induced neurodegeneration.

21 January 2018

1 reference

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Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor.

21 January 2018

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A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP.

21 January 2018

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Presynaptic kainate receptor facilitation of glutamate release involves protein kinase A in the rat hippocampus

21 January 2018

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Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains.

21 January 2018

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Differences in two mice strains on kainic acid-induced amygdalar seizures.

21 January 2018

1 reference

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Differential role of gonadal hormones on kainic acid-induced neurodegeneration in medial amygdaloid nucleus of female and male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Increased microglial activation and astrogliosis after intranasal administration of kainic acid in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Inflammatory response and glia activation in developing rat hippocampus after status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Neuroprotective effects of stanniocalcin 2 following kainic acid-induced hippocampal degeneration in ICR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Selective regulation of growth factor expression in cultured cortical astrocytes by neuro-pathological toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Increased vulnerability of hippocampal pyramidal neurons to the toxicity of kainic acid in OASIS-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Glutamate excess and free radical formation during and following kainic acid-induced status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Prostaglandin E2 produced by late induced COX-2 stimulates hippocampal neuron loss after seizure in the CA3 region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Cyclooxygenase-2 expression is induced in rat brain after kainate-induced seizures and promotes neuronal death in CA3 hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

IL-12p35 deficiency alleviates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Expression of cytokines and cytokine receptors in the rat brain after kainic acid-induced seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Seizure susceptibility to various convulsant stimuli of knockout interleukin-6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

IL-18 deficiency aggravates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice due to an overcompensation by IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

TGF-beta 1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Kainate treatment alters TGF-beta3 gene expression in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

TNF-alpha receptor 1 deficiency enhances kainic acid-induced hippocampal injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo

21 January 2018

1 reference

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Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

21 January 2018

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Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus.

21 January 2018

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Excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57BL/6 mice

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F457079

Nasal route for direct delivery of solutes to the central nervous system: fact or fiction?

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F457079

Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the molecular weight of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Melatonin attenuates kainic acid-induced hippocampal neurodegeneration and oxidative stress through microglial inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Ablation of p27 enhance kainate-induced seizure and hippocampal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Kainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Genetic background regulates semaphorin gene expression and epileptogenesis in mouse brain after kainic acid status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F457079

Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992819

Quantitative immunochemistry on neuronal loss, reactive gliosis and BBB damage in cortex/striatum and hippocampus/amygdala after systemic kainic acid administration

27 October 2018

1 reference

12 December 2020

IL-6 is required for the development of Th1 cell-mediated murine colitis

1 reference

12 December 2020

Ischemia-Induced Interleukin-6 as a Potential Endogenous Neuroprotective Cytokine against NMDA Receptor-Mediated Excitoxicity in the Brain

1 reference

12 December 2020

Glufosinate ammonium stimulates nitric oxide production through N-methyl D-aspartate receptors in rat cerebellum

1 reference

12 December 2020

Differential Expression of S100β and Glial Fibrillary Acidic Protein in the Hippocampus after Kainic Acid-Induced Lesions and Mossy Fiber Sprouting in Adult Rat

1 reference

12 December 2020

Oxidative stress is involved in seizure-induced neurodegeneration in the kindling model of epilepsy

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/457079

1 reference

1 August 2017

1 reference

1 August 2017

1 reference