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digoxin (Q422222)

From Wikidata

plant-derived medication used in certain heart conditions

Lanoxicaps
Lanoxin
Vanoxin
Lanoxin Pediatric
Digoxin Pediatric
12beta-Hydroxydigitoxin
Digossina
Lanadicor
12β-hydroxydigitoxin
Digazolan
Digoxin
Digoxina
Digoxine
Digoxinum
Digacin
Davoxin
Homolle'S digitalin
Eudigox
Rougoxin
Lanacrist
Dynamos
SK-Digoxin
Cardoxin
Neo-Lanicor
Lanicor
Digitalis glycoside
Cogoxin
Dilanacin
DGO621

Language	Label	Description	Also known as
default for all languages	No label defined
English	digoxin	plant-derived medication used in certain heart conditions	Lanoxicaps Lanoxin Vanoxin Lanoxin Pediatric Digoxin Pediatric 12beta-Hydroxydigitoxin Digossina Lanadicor 12β-hydroxydigitoxin Digazolan Digoxin Digoxina Digoxine Digoxinum Digacin Davoxin Homolle'S digitalin Eudigox Rougoxin Lanacrist Dynamos SK-Digoxin Cardoxin Neo-Lanicor Lanicor Digitalis glycoside Cogoxin Dilanacin DGO621

Statements

type of chemical entity

0 references

cardiac glycoside

1 reference

27 February 2018

0 references

1 reference

Digoxin (English)

language of work or name

publication date

17 November 2015

chemical structure

Digoxin structure.png
1,355 × 590; 18 KB

1 reference

imported from Wikimedia project

German Wikipedia

Digoxin.svg
2,800 × 1,145; 53 KB

0 references

image of molecular model or crystal lattice model

Digon ball-and-stick.png
1,999 × 1,319; 297 KB

ball-and-stick model

0 references

associated hazard

digoxin toxicity

0 references

chemical formula

C₄₁H₆₄O₁₄

1 reference

language of work or name

digoxin (English)

19 November 2016

canonical SMILES

CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

1 reference

language of work or name

digoxin (English)

19 November 2016

isomeric SMILES

C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

1 reference

language of work or name

digoxin (English)

19 November 2016

defined daily dose

0.25 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C01AA05

0.25 milligram

route of administration

parenteral route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C01AA05

active ingredient in

1 reference

14 February 2018

1 reference

14 February 2018

1 reference

14 February 2018

World Health Organisation international non-proprietary name

digoxin (English)

2 references

language of work or name

digoxin (English)

19 October 2016

Recommended INN: List 3

publication date

1959

Digitalis lanata

14 references

Long-Term Cultivation of Digitalis lanata Clones Propagated in Vitro: Cardenolide Content of the Regenerated Plants1.

Quantitative determination of cardiac glycosides in Digitalis lanata leaves by reversed-phase thin-layer chromatography

Isolation and quantitative determination of some cardioactive glycosides from Digitalis lanata by high-performance liquid chromatography

Immobilized plant cells for the production and transportation of natural products

Determination of some cardiac glycosides by high-performance liquid chromatography

Isolation of cardenolides from a Brazilian cultivar of Digitalis lanata by rotation locular counter-current chromatography

The production of secondary metabolites by Digitalis lanata during CO2 enrichment and water stress

Acetyl coenzyme A: Digitoxin 15′-O-acetyltransferase from Digitalis plants and suspension cultures

Variation of cardenolides with growth in a Digitalis lanata Brazilian cultivar

Determination of Lanatoside C and Digoxin in Digitalis lanata by Hplc and Its Application to Analysis of the Fermented Leaf Powder

Extraction and quantitation of digoxin and acetyldigoxin from the Digitalis lanata leaf via near-supercritical methanol-modified carbon dioxide

Cardenolide Biosynthesis in Foxglove1

Cardenolide and Neutral Lipid Biosynthesis from Malonate in Digitalis lanata

Growth and digoxin content in Digitalis lanata in controlled conditions and natural environment

Digitalis obscura

1 reference

Cardenolides of Digitalis obscura: The effect of phosphate and manganese on growth and productivity of shoot-tip cultures

Digitalis parviflora

1 reference

Biosynthesis of digitalis glycosides. Enzymatic glucosylation of digitoxin by particle enzyme fractions of Digitalis purpurea

Digitalis viridiflora

1 reference

Biosynthesis of digitalis glycosides. Enzymatic glucosylation of digitoxin by particle enzyme fractions of Digitalis purpurea

medical condition treated

atrial fibrillation

2 references

language of work or name

13 December 2016

Drug Indications Extracted from FAERS

2 October 2018

congestive heart failure

2 references

language of work or name

13 December 2016

Drug Indications Extracted from FAERS

2 October 2018

supraventricular tachycardia

1 reference

language of work or name

13 December 2016

heart arrhythmia

1 reference

Drug Indications Extracted from FAERS

2 October 2018

significant drug interaction

(RS)-metoprolol

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-metoprolol

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

third-degree atrioventricular block

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

atrioventricular block

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-propafenone

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-propafenone

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-propafenone

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-bendroflumethiazide

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-bendroflumethiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-bendroflumethiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(RS)-bendroflumethiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

third-degree atrioventricular block

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

third-degree atrioventricular block

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

heart arrhythmia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

ATPase Na+/K+ transporting subunit alpha 1

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

pregnancy category

Australian pregnancy category A

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

780.43 dalton

1 reference

language of work or name

digoxin (English)

19 October 2016

subject has role

enzyme inhibitor

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

15 March 2018

antiarrhythmic agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

essential medicine

0 references

Commons category

Digoxin

0 references

Identifiers

National Library of Israel J9U ID

987007555312405171

0 references

Library of Congress authority ID

0 references

InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

1 reference

language of work or name

digoxin (English)

19 November 2016

LTMHDMANZUZIPE-PUGKRICDSA-N

2 references

language of work or name

digoxin (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

LTMHDMANZUZIPE-PUGKRICDSA-N

CAS Common Chemistry

10 April 2021

https://commonchemistry.cas.org/detail?cas_rn=20830-75-5

1 reference

language of work or name

digoxin (English)

19 October 2016

2 references

language of work or name

digoxin (English)

19 November 2016

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

Reaxys registry number

77011

1 reference

language of work or name

digoxin (English)

19 October 2016

mapping relation type

3 references

language of work or name

DIGOXIN (English)

19 November 2016

ChEBI release 2019-10-02

matched by identifier from

International Chemical Identifier

InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

1 reference

language of work or name

DIGOXIN (English)

19 November 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

UniChem compound ID

1 reference

1 reference

Cambridge Structural Database

10 January 2023

based on heuristic

1 reference

Cambridge Structural Database

10 January 2023

based on heuristic

MassBank accession ID

MSBNK-Waters-WA000561

0 references

MSBNK-Waters-WA000562

0 references

MSBNK-Waters-WA000563

0 references

MSBNK-Waters-WA000564

0 references

CAMEO Chemicals ID

0 references

1 reference

imported from Wikimedia project

German Wikipedia

1 reference

Hazardous Substances Data Bank

publication date

28 October 2019

Digoxin (English)

10 May 2021

DSSTox substance ID

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Digoxin (English)

CAS no.: 20830-75-5 (English)

1 reference

language of work or name

Digoxin (English)

publication date

17 November 2015

World Health Organisation international non-proprietary name numeric ID

0 references

Guide to Pharmacology Ligand ID

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

digoxin (English)

19 November 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

5 February 2021

MeSH descriptor ID

subject named as

Digoxin

0 references

MeSH concept ID

0 references

D04.210.500.155.580.130.500.436

broader concept

Digitalis glycosides

0 references

D04.210.500.155.580.130.688

broader concept

0 references

D09.408.180.261.436

broader concept

Digitalis glycosides

0 references

1 reference

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

1 reference

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

Human Metabolome Database ID

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

reason for deprecated rank

cannot be confirmed by other sources

1 reference

language of work or name

digoxin (English)

19 October 2016

2 references

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

matched by identifier from

LTMHDMANZUZIPE-PUGKRICDSA-N

MedlinePlus drug identifier

0 references

1 reference

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

Probes And Drugs ID

0 references

1 reference

1 reference

language of work or name

digoxin (English)

19 October 2016

1 reference

language of work or name

digoxin (English)

19 October 2016

1 reference

http://www.lipidmaps.org/rest/compound/lm_id/LM/all/download

15 January 2022

LTMHDMANZUZIPE-PUGKRICDSA-N

IEDB Epitope ID

1 reference

Immune Epitope Database and Analysis Resource

IEDB Epitope ID

1 January 2022

0 references

electronic Essential Medicines List medicine ID

0 references

Encyclopædia Britannica Online ID

science/digoxin

subject named as

digoxin

0 references

science/digitalis

subject named as

digitalis

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Gran Enciclopèdia Catalana ID

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0 references

Microsoft Academic ID (discontinued)

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

Protein Data Bank

PDB structure ID

language of work or name

3B0W (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

1IGJ (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

4RET (English)

19 October 2016

1 reference

Römpp online ID

1 reference

imported from Wikimedia project

German Wikipedia

1 reference

Global Substance Registration System

language of work or name

digoxin (English)

19 November 2016

WikiProjectMed ID

0 references

WordNet 3.1 Synset ID

1 reference

Sitelinks

Wikipedia(41 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(1 entry)

itwikiquote Digossina

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Digoxin

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