GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism (Q42130341)

17 October 2017

GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism (English)

1 reference

Mycobacterium tuberculosis

17 October 2017

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author

Steffen Klamt

8

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17 October 2017

9

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17 October 2017

Graham Stewart

3

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Johnjoe McFadden

object named as

Johnjoe McFadden

10

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author name string

Dany J V Beste

1

1 reference

17 October 2017

Tracy Hooper

2

1 reference

17 October 2017

Bhushan Bonde

4

1 reference

17 October 2017

Claudio Avignone-Rossa

5

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17 October 2017

Michael E Bushell

6

1 reference

17 October 2017

Paul Wheeler

7

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17 October 2017

1 January 2007

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17 October 2017

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17 October 2017

8

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17 October 2017

R89

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17 October 2017

5

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https://scigraph.springernature.com/pub.10.1186/gb-2007-8-5-r89

17 October 2017

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Control of iron metabolism in Mycobacterium tuberculosis

29 May 2018

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M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs)

29 May 2018

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Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis

29 May 2018

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rmlB and rmlC genes are essential for growth of mycobacteria

29 May 2018

1 reference

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Carbon metabolism of intracellular bacteria

29 May 2018

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Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide

29 May 2018

1 reference

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Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis.

29 May 2018

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All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis

29 May 2018

1 reference

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Flux balance analysis of mycolic acid pathway: targets for anti-tubercular drugs

29 May 2018

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Isocitrate lyase activity is required for virulence of the intracellular pathogen Rhodococcus equi

29 May 2018

1 reference

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Function of the cytochrome bc1-aa3 branch of the respiratory network in mycobacteria and network adaptation occurring in response to its disruption

29 May 2018

1 reference

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The dimycocerosate ester polyketide virulence factors of mycobacteria.

29 May 2018

1 reference

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Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism

29 May 2018

1 reference

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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

29 May 2018

1 reference

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HemZ is essential for heme biosynthesis in Mycobacterium tuberculosis

29 May 2018

1 reference

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Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation

29 May 2018

1 reference

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Compiling a molecular inventory for Mycobacterium bovis BCG at two growth rates: evidence for growth rate-mediated regulation of ribosome biosynthesis and lipid metabolism

29 May 2018

1 reference

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Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv

29 May 2018

1 reference

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The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis

29 May 2018

1 reference

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Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis

29 May 2018

1 reference

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Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells

29 May 2018

1 reference

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Tuberculosis - metabolism and respiration in the absence of growth

29 May 2018

1 reference

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Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery

29 May 2018

1 reference

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Tuberculosis: a problem with persistence

29 May 2018

1 reference

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The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence

29 May 2018

1 reference

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Molecular genetics of Mycobacterium tuberculosis in relation to the discovery of novel drugs and vaccines

29 May 2018

1 reference

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TB drug discovery: addressing issues of persistence and resistance

29 May 2018

1 reference

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Mycothiol Is Essential for Growth ofMycobacterium tuberculosisErdman

29 May 2018

1 reference

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Genetic requirements for mycobacterial survival during infection

29 May 2018

1 reference

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ENZYME SYSTEMS IN THE MYCOBACTERIA. XV. INITIAL STEPS IN THE METABOLISM OF GLYCEROL

29 May 2018

1 reference

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An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

29 May 2018

1 reference

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The respiratory chain of Corynebacterium glutamicum.

29 May 2018

1 reference

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Vaccine efficacy of a lysine auxotroph of Mycobacterium tuberculosis

29 May 2018

1 reference

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A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis

29 May 2018

1 reference

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The global situation of MDR-TB.

29 May 2018

1 reference

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The growing burden of tuberculosis: global trends and interactions with the HIV epidemic

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Genes required for mycobacterial growth defined by high density mutagenesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Mannose metabolism is required for mycobacterial growth

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Sulfotransferases and sulfatases in mycobacteria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Genome-scale metabolic model of Helicobacter pylori 26695.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F(420) and FO biosynthesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The burden of drug-resistant tuberculosis and mechanisms for its control

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Nonreplicating persistence of mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The glyoxylate cycle is required for fungal virulence

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Learning from the genome sequence of Mycobacterium tuberculosis H37Rv

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Systems properties of the Haemophilus influenzae Rd metabolic genotype

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Toward metabolic phenomics: analysis of genomic data using flux balances

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

NADH dehydrogenase defects confer isoniazid resistance and conditional lethality in Mycobacterium smegmatis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Biochemistry and molecular genetics of cell-wall lipid biosynthesis in mycobacteria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The Mycobacterium tuberculosis purine biosynthetic pathway: isolation and characterization of the purC and purL genes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Kinetics of the simultaneous utilization of sugar mixtures by Escherichia coli in continuous culture.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Initial steps in the metabolism of glycerol by Mycobacterium tuberculosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Phenolic glycolipids of Mycobacterium bovis: new structures and synthesis of a corresponding seroreactive neoglycoprotein

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Glycerol dissimilation and its regulation in bacteria

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The glyoxylate cycle enzyme activities in the pathogenic isolates of Candida albicans obtained from HIV/AIDS, diabetic and burn patients

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The pyruvate requirement of some members of the Mycobacterium tuberculosis complex is due to an inactive pyruvate kinase: implications for in vivo growth

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The glyoxylate cycle is required for temporal regulation of virulence by the plant pathogenic fungus Magnaporthe grisea

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

Up-regulation of narX, encoding a putative 'fused nitrate reductase' in anaerobic dormant Mycobacterium bovis BCG.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929162

The physiology of erythromycin biosynthesis in cyclic fed batch culture

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17521419

12 December 2020

inferred from PubMed ID database lookup

Lipid lunch for persistent pathogen

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17521419

12 December 2020

inferred from PubMed ID database lookup

Production of actinorhodin by Streptomyces coelicolor A3(2) grown in chemostat culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17521419

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/GB-2007-8-5-R89

1 reference

Dimensions Publication ID

17 October 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/gb-2007-8-5-r89

Fatcat ID

release_j4rzfr3dtbaftboxcbhbkzbnpu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j4rzfr3dtbaftboxcbhbkzbnpu

24 November 2022

mapped directly with Wikidata item

1 reference

17 October 2017

1 reference