TB drug discovery: addressing issues of persistence and resistance (Q35605919)

9 August 2017

1 reference

title

TB drug discovery: addressing issues of persistence and resistance (English)

1 reference

9 August 2017

1 reference

Clare V Smith

1

1 reference

PubMed ID

14670345

9 August 2017

Vivek Sharma

series ordinal

2

1 reference

PubMed ID

14670345

9 August 2017

James C Sacchettini

series ordinal

3

1 reference

9 August 2017

1 January 2004

1 reference

9 August 2017

1 reference

9 August 2017

84

1 reference

9 August 2017

1-2

1 reference

9 August 2017

45-55

1 reference

Mechanisms of latency in Mycobacterium tuberculosis

9 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Mycobacterial persistence: adaptation to a changing environment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Spread of strain W, a highly drug-resistant strain of Mycobacterium tuberculosis, across the United States

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Erasing the World's Slow Stain: Strategies to Beat Multidrug-Resistant Tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Identification of Mycobacterium tuberculosis RNAs synthesized in response to phagocytosis by human macrophages by selective capture of transcribed sequences (SCOTS)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

3D domain swapping: a mechanism for oligomer assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Massive gene decay in the leprosy bacillus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

2-Methylisocitrate lyases from the bacterium Escherichia coli and the filamentous fungus Aspergillus nidulans: characterization and comparison of both enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The structure and domain organization of Escherichia coli isocitrate lyase

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

inferred from DOI database lookup

7 January 2021

based on heuristic

The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Crystal structure of Escherichia coli malate synthase G complexed with magnesium and glyoxylate at 2.0 A resolution: mechanistic implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Mycolic acids: structure, biosynthesis and physiological functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Identification of a gene involved in the biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

MMAS-1, the branch point between cis- and trans-cyclopropane-containing oxygenated mycolates in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Cyclopropane fatty acid synthase of Escherichia coli: deduced amino acid sequence, purification, and studies of the enzyme active site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

HhaI methyltransferase flips its target base out of the DNA helix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Universal catalytic domain structure of AdoMet-dependent methyltransferases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

AdoMet-dependent methylation, DNA methyltransferases and base flipping

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

A common mechanism for the biosynthesis of methoxy and cyclopropyl mycolic acids in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Crystal structure of catechol O-methyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The biosynthesis of mycolic acids in Mycobacterium tuberculosis. Enzymatic methyl(ene) transfer to acyl carrier protein bound meromycolic acid in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

The glyoxylate cycle is required for fungal virulence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.019

10.1016/J.TUBE.2003.08.019

7 January 2021

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14670345