Hypoxic regulation of the noncoding genome and NEAT1. (Q42070258)

16 October 2017

1 reference

30 April 2021

Hypoxic regulation of the noncoding genome and NEAT1. (English)

1 reference

neoplastic gene expression regulation

16 October 2017

1 reference

30 April 2021

1 reference

4 November 2020

1 reference

17 November 2020

1 reference

8 February 2021

1 reference

30 April 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

David Robert Mole

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1

Hani Choudhry

1 reference

16 October 2017

2

David R Mole

1 reference

16 October 2017

language of work or name

1 reference

20 November 2015

1 reference

Briefings in functional genomics

16 October 2017

1 May 2016

8 references

14 March 2019

3 April 2019

8 September 2019

7 October 2019

4 November 2020

17 November 2020

8 February 2021

30 April 2021

9 references

14 March 2019

3 April 2019

8 September 2019

7 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

4 November 2020

17 November 2020

8 February 2021

30 April 2021

15

1 reference

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7 June 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

174-185

1 reference

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Creative Commons Attribution 4.0 International

7 June 2020

copyright license

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14 March 2019

3 April 2019

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7 October 2019

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on focus list of Wikimedia project

30 April 2021

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells

5 June 2018

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5 June 2018

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5 June 2018

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

5 June 2018

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5 June 2018

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The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth

5 June 2018

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Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling

5 June 2018

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5 June 2018

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5 June 2018

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MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia

5 June 2018

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A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like

5 June 2018

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5 June 2018

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Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis

5 June 2018

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Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells

5 June 2018

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MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1)

5 June 2018

1 reference

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Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis

5 June 2018

1 reference

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MicroRNA-210 as a novel therapy for treatment of ischemic heart disease

5 June 2018

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The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

5 June 2018

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5 June 2018

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5 June 2018

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P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

5 June 2018

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MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis

5 June 2018

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miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells.

5 June 2018

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5 June 2018

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Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

5 June 2018

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5 June 2018

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Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration.

5 June 2018

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Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia

5 June 2018

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Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA

5 June 2018

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HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses

5 June 2018

1 reference

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MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT.

5 June 2018

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Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

5 June 2018

1 reference

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Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis

5 June 2018

1 reference

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Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes

5 June 2018

1 reference

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Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

5 June 2018

1 reference

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An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

5 June 2018

1 reference

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MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles

5 June 2018

1 reference

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MicroRNA regulation of DNA repair gene expression in hypoxic stress

5 June 2018

1 reference

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MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

5 June 2018

1 reference

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HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

5 June 2018

1 reference

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Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210.

5 June 2018

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

5 June 2018

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Alu element-mediated gene silencing

5 June 2018

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MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

The H19 non-coding RNA is essential for human tumor growth

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

A microRNA signature of hypoxia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Regulating gene expression through RNA nuclear retention

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Integration of oxygen signaling at the consensus HRE.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Regulation of transcription and translation by hypoxia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

MicroRNAs: small RNAs with a big role in gene regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Oxygen sensing by HIF hydroxylases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus

5 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

5 June 2018

https://api.crossref.org/works/10.1093%2FBFGP%2FELV050

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Mutations of the VHL tumour suppressor gene in renal carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Tumor hypoxia and malignant progression.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FBFGP%2FELV050

Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FBFGP%2FELV050

Hypoxia-inducible Expression of a Naturalcis-Antisense Transcript Inhibits Endothelial Nitric-oxide Synthase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FBFGP%2FELV050

Characterization of novel antisense HIF-1α transcripts in human cancers

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4880005

The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26590207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26590207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of long noncoding RNA MALAT1 in hypoxic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26590207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/BFGP/ELV050

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

26590207

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590207%20AND%20SRC:MED&resulttype=core&format=json