Selective reconstitution and recovery of functional gamma-secretase complex on budded baculovirus particles (Q42044384)

15 October 2017

Selective reconstitution and recovery of functional gamma-secretase complex on budded baculovirus particles (English)

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15 October 2017

7

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15 October 2017

Ikuo Hayashi

1

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15 October 2017

Yasuomi Urano

2

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15 October 2017

Rie Fukuda

3

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15 October 2017

Noriko Isoo

4

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15 October 2017

Tatsuhiko Kodama

5

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15 October 2017

Takao Hamakubo

6

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15 October 2017

Takeshi Iwatsubo

8

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15 October 2017

language of work or name

English

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publication date

23 June 2004

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Journal of Biological Chemistry

15 October 2017

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15 October 2017

279

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15 October 2017

38040-38046

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15 October 2017

36

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G protein-coupled receptor overexpression with the baculovirus-insect cell system: a tool for structural and functional studies.

15 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus. Evidence for Galpha and Galphao coupling to a human leukotriene B4 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

A novel method for viral display of ER membrane proteins on budded baculovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Therapeutic strategies for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

The role of presenilin cofactors in the gamma-secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Solid-phase synthesis of photoaffinity probes: highly efficient incorporation of biotin-tag and cross-linking groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

The mechanism of gamma-secretase activities through high molecular weight complex formation of presenilins is conserved in Drosophila melanogaster and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

The role of presenilin-1 in the gamma-secretase cleavage of the amyloid precursor protein of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Assembly and activation of the γ-secretase complex: roles of presenilin cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the Abeta 42-promoting effects of Alzheimer mutant presenilin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Autographa californica nuclear polyhedrosis virus, PDV, and ECV viral envelopes and nucleocapsids: structural proteins, antigens, lipid and fatty acid profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Membrane lipid metabolism and phospholipase activity in insect Spodoptera frugiperda 9 ovarian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Lipid composition of Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) insect cells used for baculovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Palmitoylation of the Autographa californica multicapsid nucleopolyhedrovirus envelope glycoprotein GP64: mapping, functional studies, and lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Pathogens: raft hijackers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

Determination of the protein composition of the occlusion-derived virus of Autographa californica nucleopolyhedrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405597200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405597200

1 reference

15 October 2017

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