Nucleophile activation in PD...(D/E)xK metallonucleases: an experimental and computational pK(a) study (Q41968683)

14 October 2017

Nucleophile activation in PD...(D/E)xK metallonucleases: an experimental and computational pK(a) study (English)

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14 October 2017

Fuqian Xie

1

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14 October 2017

James M Briggs

series ordinal

2

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14 October 2017

Cynthia M Dupureur

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3

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14 October 2017

language of work or name

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6 March 2010

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Journal of Inorganic Biochemistry

14 October 2017

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14 October 2017

104

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14 October 2017

6

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14 October 2017

665-672

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describes a project that uses

14 October 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2913505/fullTextXML

inferred from PubMed Central ID database lookup

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Structural and biochemical characterization of a new Mg(2+) binding site near Tyr94 in the restriction endonuclease PvuII

5 June 2018

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5 June 2018

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pKa calculations suggest storage of an excess proton in a hydrogen-bonded water network in bacteriorhodopsin

5 June 2018

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5 June 2018

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Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques: multiple electrostatic modulators of active-centre chemistry

5 June 2018

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5 June 2018

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PvuII endonuclease contains two calcium ions in active sites

5 June 2018

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A self-consistent, microenvironment modulated screened coulomb potential approximation to calculate pH-dependent electrostatic effects in proteins

5 June 2018

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Divalent metal dependence of site-specific DNA binding by EcoRV endonuclease.

5 June 2018

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Catalytic roles of divalent metal ions in phosphoryl transfer by EcoRV endonuclease

5 June 2018

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Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases

5 June 2018

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5 June 2018

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5 June 2018

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pKa calculations for class A beta-lactamases: methodological and mechanistic implications

5 June 2018

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Prediction of pH-dependent properties of proteins

5 June 2018

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Environmental effects on the protonation states of active site residues in bacteriorhodopsin

5 June 2018

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pH, ionic strength, and temperature dependences of ionization equilibria for the carboxyl groups in turkey ovomucoid third domain.

5 June 2018

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5 June 2018

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One- and two-metal ion catalysis: global single-turnover kinetic analysis of the PvuII endonuclease mechanism

5 June 2018

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Probing the two-metal ion mechanism in the restriction endonuclease BamHI.

18 August 2018

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DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites.

18 August 2018

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The determinants of alpha-amylase pH-activity profiles.

18 August 2018

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The determinants of pKas in proteins

18 August 2018

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Plasmid DNA Cleavage byMunI Restriction Enzyme: Single-Turnover and Steady-State Kinetic Analysis†

18 August 2018

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A site-directed mutagenesis study to identify amino acid residues involved in the catalytic function of the restriction endonuclease EcoRV

2 December 2018

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12 December 2020

A catalytically deficient active site variant of PvuII endonuclease binds Mg(II) ions

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12 December 2020

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12 December 2020

Preparation of metal-free enzymes

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12 December 2020

Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis

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12 December 2020

pKa analysis for the zinc-bound water in human carbonic anhydrase II: Benchmark for "multiscale" QM/MM simulations and mechanistic implications

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12 December 2020

On the calculation of pKas in proteins

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12 December 2020

pK(a) calculations for class C beta-lactamases: the role of Tyr-150

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12 December 2020

Quantitative evaluation of metal ion binding to PvuII restriction endonuclease

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12 December 2020

Effects of divalent metal ions on the activity and conformation of native and 3-fluorotyrosine-PvuII endonucleases

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12 December 2020

Buffers of constant ionic strength for studying pH-dependent processes

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12 December 2020

Experimental and theoretical study of electrostatic effects on the isoelectric pH and the pKa of the catalytic residue His-102 of the recombinant ribonuclease from Bacillus amyloliquefaciens (barnase)

1 reference

12 December 2020

Dissecting the metal ion dependence of DNA binding by PvuII endonuclease

1 reference

12 December 2020

Probing the general base catalysis in the first step of BamHI action by computer simulations

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12 December 2020

Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

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12 December 2020

Multiple-site titration and molecular modeling: two rapid methods for computing energies and forces for ionizable groups in proteins

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12 December 2020

Catalytic and DNA binding properties of PvuII restriction endonuclease mutants

1 reference

12 December 2020

10.1016/J.JINORGBIO.2010.02.008

Identifiers

DOI

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14 October 2017

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14 October 2017

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