Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs). (Q41910192)

14 October 2017

1 reference

title

Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs). (English)

1 reference

14 October 2017

Chiara Porta

2

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author name string

Antonio Sica

1

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14 October 2017

Sara Morlacchi

3

1 reference

14 October 2017

Stefania Banfi

4

1 reference

14 October 2017

Laura Strauss

5

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14 October 2017

Monica Rimoldi

6

1 reference

14 October 2017

Maria Grazia Totaro

7

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14 October 2017

Elena Riboldi

8

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14 October 2017

24 September 2011

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14 October 2017

Cancer Microenvironment

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14 October 2017

5

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14 October 2017

133-149

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14 October 2017

2

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https://scigraph.springernature.com/pub.10.1007/s12307-011-0091-6

14 October 2017

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

5 June 2018

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Subsets of myeloid-derived suppressor cells in tumor-bearing mice

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

5 June 2018

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5 June 2018

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5 June 2018

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Bv8 regulates myeloid-cell-dependent tumour angiogenesis

5 June 2018

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HIF gene expression in cancer therapy

5 June 2018

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RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia

5 June 2018

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The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

5 June 2018

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A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis

5 June 2018

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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

5 June 2018

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A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model

5 June 2018

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Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

5 June 2018

1 reference

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Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

5 June 2018

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Altered macrophage differentiation and immune dysfunction in tumor development

5 June 2018

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Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

5 June 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

5 June 2018

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Hypoxia in cancer: significance and impact on clinical outcome

5 June 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

5 June 2018

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

5 June 2018

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Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

The role of cytokines in hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Nuclear factor-kappaB in cancer development and progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Monocyte and macrophage heterogeneity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Inflammation and cancer: is the link as simple as we think?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Macrophage arginase regulation by CCAAT/enhancer-binding protein beta.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Cancer and the chemokine network

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Tumour-educated macrophages promote tumour progression and metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Infiltration of neutrophils is required for acquisition of metastatic phenotype of benign murine fibrosarcoma cells: implication of inflammation-associated carcinogenesis and tumor progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Regulation of the chemokine receptor CXCR4 by hypoxia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Blood monocytes consist of two principal subsets with distinct migratory properties

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

The macrophage growth factor CSF-1 in mammary gland development and tumor progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Signalling heterogeneity as a contributing factor in macrophage functional diversity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Inhibition of tumor growth by elimination of granulocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Characterization of lipopolysaccharide-induced macrophage gene expression.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

The yin-yang of tumor-associated neutrophils.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

SHIP represses the generation of alternatively activated macrophages

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399067

p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

18 August 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0091-6

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0091-6

Never Underestimate the Power of a Neutrophil

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0091-6

Convergent pathways of macrophage polarization: The role of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0091-6

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12307-011-0091-6

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

21 January 2018

1 reference

12 December 2020

Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14⁻/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer

1 reference

12 December 2020

Up-regulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function

1 reference

12 December 2020

STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion

1 reference

12 December 2020

Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response

1 reference

12 December 2020

Macrophage inflammatory protein-1 alpha expression in non-neoplastic and neoplastic lung tissue

1 reference

12 December 2020

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

12 December 2020

Alpha1-antitrypsin and neutrophil elastase imbalance and lung cancer risk

1 reference

12 December 2020

Significance of M2-polarized tumor-associated macrophage in pancreatic cancer

1 reference

12 December 2020

Expression of Tie-2 by human monocytes and their responses to angiopoietin-2

1 reference

12 December 2020

Differential regulation of gene expression during macrophage activation with a polyribonucleotide. The role of endogenously derived IFN

1 reference

12 December 2020

Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign

1 reference

12 December 2020

Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences

1 reference

12 December 2020

Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF- B Activation in Tumor-Associated Macrophages

1 reference

12 December 2020

Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma

1 reference

12 December 2020

Regulation of the macrophage content of neoplasms by chemoattractants

1 reference

12 December 2020

10.1007/S12307-011-0091-6

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference