A regio- and stereoselective ω-transaminase/monoamine oxidase cascade for the synthesis of chiral 2,5-disubstituted pyrrolidines (Q41870013)

13 October 2017

A regio- and stereoselective ω-transaminase/monoamine oxidase cascade for the synthesis of chiral 2,5-disubstituted pyrrolidines (English)

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13 October 2017

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7

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13 October 2017

Elaine O'Reilly

1

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James L Galman

object named as

James L Galman

5

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Cesar Iglesias

object named as

Cesar Iglesias

2

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author name string

Diego Ghislieri

3

1 reference

13 October 2017

Jennifer Hopwood

4

1 reference

13 October 2017

Richard C Lloyd

6

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13 October 2017

language of work or name

English

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publication date

29 January 2014

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Angewandte Chemie International Edition

13 October 2017

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volume

53

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13 October 2017

9

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13 October 2017

2447-2450

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Biocatalysis in organic chemistry and biotechnology: past, present, and future

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Enzyme catalysed tandem reactions.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Engineering the third wave of biocatalysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Draft genome sequence of the anaerobic, nitrate-dependent, Fe(II)-oxidizing bacterium Pseudogulbenkiania ferrooxidans strain 2002

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Recent biocatalytic oxidation-reduction cascades

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

omega-Transaminases for the synthesis of non-racemic alpha-chiral primary amines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Pd-catalyzed carboamination of oxazolidin-2-ones: a stereoselective route to trans-2,5-disubstituted pyrrolidines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Directed evolution drives the next generation of biocatalysts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Asymmetric synthesis of trans-2,5-disubstituted pyrrolidines from enantiopure homoallylic amines. Synthesis of pyrrolidine (-)-197B

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Biocatalytic retrosynthesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Enantioselective, palladium-catalyzed alpha-arylation of N-Boc-pyrrolidine

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Palladium-catalyzed DYKAT of vinyl epoxides: enantioselective total synthesis and assignment of the configuration of (+)-Broussonetine G.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Total synthesis of A-315675: a potent inhibitor of influenza neuraminidase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Directed evolution of an amine oxidase possessing both broad substrate specificity and high enantioselectivity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227563

Directed Evolution of the Enzyme Monoamine Oxidase (MAO-N): Highly Efficient Chemo-enzymatic Deracemisation of the Alkaloid (±)-Crispine A

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201309208

Monoamine Oxidase (MAO-N) Catalyzed Deracemization of Tetrahydro-β-carbolines: Substrate Dependent Switch in Enantioselectivity

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201309208

A concise asymmetric route to the bridged bicyclic tropane alkaloid ferruginine using enyne ring-closing metathesis

21 January 2018

1 reference

12 December 2020

Efficient, chemoenzymatic process for manufacture of the Boceprevir bicyclic [3.1.0]proline intermediate based on amine oxidase-catalyzed desymmetrization

1 reference

12 December 2020

General strategy for the construction of enantiopure pyrrolidine-based alkaloids. Total synthesis of (-)-monomorine

1 reference

12 December 2020

Heck arylation of endocyclic enecarbamates with diazonium salts. Improvements and a concise enantioselective synthesis of (-)-codonopsinine

1 reference

12 December 2020

Regio- and Stereoselective Monoamination of Diketones without Protecting Groups

1 reference

12 December 2020

Asymmetric synthesis of cis- and trans-2,5-disubstituted pyrrolidines from 3-oxo pyrrolidine 2-phosphonates: synthesis of (+)-preussin and analogs

1 reference

12 December 2020

Application of intramolecular enyne metathesis to the synthesis of aza[4.2.1]bicyclics: enantiospecific total synthesis of (+)-anatoxin-a

1 reference

12 December 2020

Redox Self-Sufficient Biocatalyst Network for the Amination of Primary Alcohols

1 reference

12 December 2020

Iterative organometallic addition to chiral hydroxylated cyclic nitrones: highly stereoselective syntheses of alpha,alpha'- and alpha,alpha-substituted hydroxypyrrolidines

1 reference

12 December 2020

trans-2,5-Disubstituted pyrrolidines: Rapid stereocontrolled access from sulfones

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANIE.201309208

1 reference

release_vsrf24x5vbfjldreg4gjmrpxyq

13 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vsrf24x5vbfjldreg4gjmrpxyq

24 November 2022

mapped directly with Wikidata item

1 reference

13 October 2017

1 reference