Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome (Q41849184)

13 October 2017

Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome (English)

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13 October 2017

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13 October 2017

Emily K Osterweil

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author name string

Kimberly Reinhold

series ordinal

3

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13 October 2017

Mark F Bear

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4

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13 October 2017

language of work or name

English

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publication date

1 November 2010

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13 October 2017

Journal of Neuroscience

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13 October 2017

30

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13 October 2017

15616-15627

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13 October 2017

46

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describes a project that uses

13 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3400430/fullTextXML

inferred from PubMed Central ID database lookup

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18 August 2018

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18 August 2018

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18 August 2018

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12 December 2020

Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation

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12 December 2020

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

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12 December 2020

Evidence that fragile X mental retardation protein is a negative regulator of translation

1 reference

12 December 2020

The fragile X mental retardation protein inhibits translation via interacting with mRNA

1 reference

12 December 2020

Induction of long-term depression in cerebellar Purkinje cells requires a rapidly turned over protein

1 reference

12 December 2020

Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.

1 reference

12 December 2020

Identification of sites for exponential translation in living dendrites

1 reference

12 December 2020

Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatum

1 reference

12 December 2020

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

1 reference

12 December 2020

Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

1 reference

12 December 2020

Epilepsy in fragile X syndrome.

1 reference

12 December 2020

Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus

1 reference

12 December 2020

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses

1 reference

12 December 2020

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

1 reference

12 December 2020

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

1 reference

12 December 2020

BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development.

1 reference

12 December 2020

Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translation

1 reference

12 December 2020

Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses

1 reference

12 December 2020

Phosphorylation of proteins involved in activity-dependent forms of synaptic plasticity is altered in hippocampal slices maintained in vitro

1 reference

12 December 2020

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis

1 reference

12 December 2020

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain

1 reference

12 December 2020

Differential translation and fragile X syndrome

1 reference

12 December 2020

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

1 reference

12 December 2020

Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression.

1 reference

12 December 2020

Activity-dependent regulation of NR2B translation contributes to metaplasticity in mouse visual cortex.

1 reference

12 December 2020

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression

1 reference

12 December 2020

Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities.

1 reference

12 December 2020

Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control.

1 reference

12 December 2020

Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome.

1 reference

12 December 2020

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

1 reference

12 December 2020

The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines

1 reference

12 December 2020

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

1 reference

12 December 2020

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors

1 reference

12 December 2020

Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity

1 reference

12 December 2020

Correction of fragile X syndrome in mice.

1 reference

12 December 2020

Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation

1 reference

12 December 2020

mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice

1 reference

12 December 2020

Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome

1 reference

12 December 2020

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

1 reference

12 December 2020

Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

1 reference

12 December 2020

Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory

1 reference

12 December 2020

Limbic epileptogenesis in a mouse model of fragile X syndrome

1 reference

12 December 2020

BC1 regulation of metabotropic glutamate receptor-mediated neuronal excitability.

1 reference

12 December 2020

Cytoplasmic polyadenylation element-binding protein regulates neurotrophin-3-dependent beta-catenin mRNA translation in developing hippocampal neurons

1 reference

12 December 2020

Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis

1 reference

12 December 2020

TrkA cross-linking mimics neuronal responses to nerve growth factor

1 reference

12 December 2020

Metabotropic glutamate receptors trigger postsynaptic protein synthesis

1 reference

12 December 2020

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

1 reference

12 December 2020

Requirement of protein synthesis for group I mGluR-mediated induction of epileptiform discharges

1 reference

12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

12 December 2020

10.1523/JNEUROSCI.3888-10.2010

Identifiers

DOI

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13 October 2017

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13 October 2017

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